Matthew Davis, MD

B.A. 1947, University of Wisconsin. Madison
MD. 1950, University of Pennsylvania, Philadelphia

University of Wisconsin, Madison

University of Wisconsin, Madison,

Retina Fellowship Massachusetts Eye & Ear Infirmary, Boston

Dr. Davis is the Emeritus Director of the Fundus Photograph Reading Center (FPRC), which works with various clinical research studies to analyze photographs of the retina and to assess changes over time. The mission of the FPRC is "to develop methods for assessment of ocular disorders and ocular manifestations of systemic disorders in fundus and other ocular photographs that are suitable for multi-center clinical trials and epidemiologic studies, and to collaborate in the design, conduct, and analysis of such studies." Under the guidance of Dr. Davis, several standards for "grading" the characteristics of the lens and retina have been established. The photographs of individuals receiving promising study treatments are reviewed and compared with the photographs of individuals not receiving the treatment, and an analysis of the amount, type, and rates of change can be performed in an unbiased manner. Having such a system in place provides a record of the effect of both the treatment and natural history of the condition being studied. The Fundus Photograph Reading Center is an invaluable resource for those doing research on eye conditions. The FPRC currently serves the Age-Related Eye Disease Study, a national study investigating the effects of vitamin and mineral supplements on macular degeneration and cataract, and the Studies of the Ocular Complications of AIDS which is looking at the course of cytomegalovirus retinitis, among other studies.

ORAL PROTEIN KINASE C β INHIBITION USING RUBOXISTAURIN: Efficacy, Safety, and Causes of Vision Loss Among 813 Patients (1,392 Eyes) with Diabetic Retinopathy in the Protein Kinase C β Inhibitor-Diabetic Retinopathy Study and the Protein kinase C β Inhibit
August 25, 2011

Comparison of digital and film grading of diabetic retinopathy severity in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study.
June 15, 2011

Comparison of Film and Digital Fundus Photographs in Eyes of Individuals with Diabetes Mellitus.
May 17, 2011

EFFECT OF RUBOXISTAURIN (RBX) ON VISUAL ACUITY DECLINE OVER A 6-YEAR PERIOD WITH CESSATION AND REINSTITUTION OF THERAPY: Results of an Open-Label Extension of the Protein Kinase C Diabetic Retinopathy Study 2 (PKC-DRS2).
March 10, 2011

Ethnicity, race, and clinically significant macular edema in the Veterans Affairs Diabetes Trial (VADT).
September 2, 2009

Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema.
August 19, 2008