Natural History of the Progression of X-Linked Retinitis Pigmentosa Study

Active Clinical Trials // Feb 12 2018

Natural History of the Progression of X-Linked Retinitis Pigmentosa Study (NSR-XLRP-OS1)

Multicenter Observational Study of X-Linked Retinitis Pigmentosa.

Sponsor: Night Therapeutics

Principal Investigator: Kim Stepien, MD

Study Coordinator: Nickie Stangel

Study Objective:

To gain a better understanding of disease progression over time in subjects with X-Linked retinitis pigmentosa (XLRP).

Study Design:

This is a multicenter, prospective, observational study consisting of seven visits over a 24-month period. The study will enroll two best corrective visual acuity (BCVA) cohorts, with no more than 40 subjects in Cohort 1. Cohort 1 BCVA will be better or equal to 20/32 with Cohort 2 BCVA being 20/40 – 20/200.

Diagnosis and Key Eligibility Criteria:

Are male and 16 years or older. Have a genetically confirmed diagnosis of XLRP with RPGR mutation. Have active disease clinically visible within the macular region. Have BCVA equal to or better than 20/200.

Duration of Study: 24 months

 

For more information, contact Nickie Stangel 608-263-8783.