Characterization and Management of Inflammatory Eye Disease in Patients with Hidradenitis Suppurativa.

Laura Kopplin // Publications // Nov 17 2021

PubMed ID: 32255701

Author(s): Lee DJ, Desai S, Laurent E, Kopplin LJ. Characterization and management of inflammatory eye disease in patients with hidradenitis suppurativa. Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1318-1323. doi: 10.1080/09273948.2020.1739718. Epub 2020 Apr 7. PMID 32255701

Journal: Ocular Immunology And Inflammation, Volume 29, Issue 7 8, Nov 2021

Purpose: To assess the spectrum and treatment outcomes of inflammatory eye disease (IED) in subjects with hidradenitis suppurativa (HS).Methods: We conducted a single center retrospective chart review of 236 patients with HS seen for ophthalmic examination between 2013 and 2018.Results: Of 236 subjects with HS, 22 subjects (9.3%) were found to have IED. Seven of 22 subjects had more than one IED diagnosis. Anterior uveitis was the most common type of IED (40.9% of subjects with IED). Episcleritis, optic neuritis, keratitis, scleritis, intermediate and posterior uveitis, trochleitis, and dacryoadenitis were also observed. Of subjects with HS and IED, 59.1% did not have any other inflammatory or autoimmune disease that could explain the etiology of their IED. Eleven patients with IED were treated with systemic immunosuppression, with IED as the principal factor directing treatment in three patients.Conclusions: IED may be independently associated with HS and may benefit from systemic immunosuppression.