Paul L. Kaufman, MD

Paul L. Kaufman, MD

Ernst H. Bárány Professor of Ocular Pharmacology, Department Chair Emeritus

Contact Administrative Support

  • Glaucoma, accommodation/presbyopia, intraocular pressure regulation/aqueous humor dynamics
  • Devise methods for obtaining accurate, reproducible measurements of Schlemm’s canal pressure as the gateway to the distal aqueous outflow apparatus
  • Develop gene therapies to enhance aqueous humor outflow and reduce intraocular pressure
  • Study the anatomic and pathophysiological relationship between presbyopia and glaucomatous optic neuropathy
  • Characterize all anatomical movements during accommodation (i.e., ciliary muscle, lens, sclera, choroid, vitreous fluid, vitreous membranes/fibers/strands) and their changes with age
  • Elucidate the full mechanism of accommodation and the extralenticular pathophysiology of presbyopia

Specialties:
Glaucoma

Fellowship:
Seeing Eye and National Institutes of Health Research Fellow, Departments of Pharmacology and Physiology, University of Uppsala, Uppsala, Sweden

Residency:
Washington University School of Medicine and Barnes Hospital, St. Louis, MO

Internship:
Bellevue Hospital, Columbia University Medical Division, New York, NY

Medical School:
New York University School of Medicine, New York, NY

Affiliate Appointment:
Wisconsin National Primate Research Center, Animal Health and Biomedical Sciences – School of Veterinary Medicine, Director-Glaucoma Services

Research:
Dr. Kaufman’s research centers on studies of the physiology, pharmacology, morphology, cell biology, genetic manipulation, neural control, biomechanics and aging of the aqueous humor formation and drainage and accommodative mechanisms in the non-human primate, seeking to understand the pathophysiology and develop new therapies for the human diseases of glaucoma and presbyopia.

Glaucoma is the second most common cause of irreversible visual loss in adult Americans, the most common among African Americans, and the most common world-wide, while presbyopia is the most common of all ocular afflictions.