Please join us for a collective exploration into the ever-changing landscape of sight saving discovery with colleagues and peers from across the globe.
Our next discussion will feature Janet R. Sparrow, PhD, Anthony Donn Professor of Ophthalmic Science and Pathology and Cell Biologyfrom Columbia University, New York, NY with her presentation:
Visual Cycle Adducts and Diseases of Retina
About Dr. Sparrow’s Research
Research in the laboratory has been directed toward understanding the composition of RPE lipofuscin; the structures and properties of the bisretinoid constituents of lipofuscin; mechanisms by which they form and the adverse effects of these compounds on photoreceptor cells and RPE. We also explore therapies (gene therapy and small molecules) aimed at reducing bisretinoid accumulation. The bisretinoids of retina are the source of fundus autofluorescence. Thus we are also uniquely positioned to apply our understanding of RPE bisretinoid to clinical interpretations and measurements of fundus autofluorescence in retinal disease. Taken together, the work contributions to the elucidation of pathology in several retinal disorders including recessive Stargardt disease, retinitis pigmentosa, pattern dystrophies, bull’s eye maculopathy and age-related macular degeneration.
We encourage you to join us before the program at 5pm for refreshments and networking as well.