Fundus Photograph Reading Center

Leader in Ophthalmic Image Evaluation since 1970

The Fundus Photograph Reading Center (FPRC) was founded on the enduring principles of intellectual honesty, quality, relevance, innovation and staff satisfaction. We are the core imaging lab within the University of Wisconsin – Madison Department of Ophthalmology and Visual Sciences studying diabetic retinopathy, age-related macular degeneration, uveitis and many more.

We serve a wide range of academic institutions, foundations, pharmaceutical companies and biotech firms including the National Eye Institute, National Institute of Diabetes and Digestive Kidney Diseases, Diabetic Retinopathy Clinical Research Network and the Department of Defense.

LEARN MORE ABOUT OUR DEPARTMENT HISTORY

Meet the FPRC Team

Fundus Photograph Reading Center

Barbara A. Blodi

Professor, Medical Director of the Fundus Photograph Reading Center and Clinical Trials Unit

608-263-7290

Fundus Photograph Reading Center
Fundus Photograph Reading Center

Amitha Domalpally

Ophthalmologist; Research Director of the Fundus Photograph Reading Center

608-263-1088

Fundus Photograph Reading Center
Fundus Photograph Reading Center

Michael M. Altaweel

Professor; Co-Director of the Fundus Photograph Reading Center

608-263-7290

Fundus Photograph Reading Center
Fundus Photograph Reading Center

Matthew D. Davis

Professor Emeritus; Founder of the Fundus Photograph Reading Center

608-262-1334

Fundus Photograph Reading Center

Services

For early phase clinical trials, we offer a streamlined approach tailored to the needs of the study and sponsor.

Imaging Modalities:

Optical coherence tomography angiography, quantitative autofluorescence, fundus autofluorescence, ultra-wide field imaging (color, AF, FA, OCT)

Certification and regulatory compliance:

Certify technicians and equipment, assistance with site selection at study onset

 

Workflow:

  • Consultation on protocol design
  • Defining ocular disease outcomes
  • Study protocol/start-up training
  • On Site/off Site and web based training on imaging protocols
  • Certification of photography equipment and operators
  • Project management
  • Electronic upload of digital images
  • DICOM conversion
  • Inventory tracking
  • Query monitoring
  • Image quality monitoring and reporting
  • Reproducibility reports for evaluation data
  • Collaboration on manuscript preparation
  • Storage and archival of study images

Evaluation Types

  • Diabetic retinopathy
  • Age-related macular degeneration
  • Macular Edema
  • Vein Occlusion
  • Infectious and non-infectious Uveitis
  • Cytomegalovirus retinitis
  • Lens opacities
  • Glaucoma and neurodegenerative diseases
  • Safety studies to monitor toxicity

Image Evaluations

  • Optical Coherence Tomography (quantitative and layer analysis)
  • Fundus autofluorescence (SLO and camera-based)
  • Color fundus photography
  • Fluorescein and ICG angiograms
  • Red reflex, retroillumination and slit lamp lens photographs

Regulatory Compliance

  • Independent Quality Assurance workgroup, reporting directly to the General Manager
  • FPRC Documentation is compliant with ICH (International Conference on Harmonisation) guidelines and global regulatory requirements.
  • FPRC developed software is compliant with 21 CFR Part 11, ICH and other applicable global regulatory requirements.
  • FPRC staff are trained in HIPAA, human subjects and regulatory compliance and follow a detailed set of policies and standard operating procedures (SOPs).
  • Expert FDA hearing support

Imaging

All photographers and OCT operators taking images for any of our studies will need to be certified by the UW-FPRC for each study specific procedure, before submitting actual patient photographs.

ACTIVE GRANTS

COMING SOON

recent publications

Systemic Therapy Outperforms Intraocular Implant for Treating Uveitis

May 31 2017 // Uveitis is characterized by inflammation inside the eye and is a leading cause of vision loss in the working population. The Multicenter Uveitis Steroid Treatment Trial compared the effectiveness and risks of systemic therapy consisting… Read More

Systemic Therapy Outperforms Intraocular Implant for Treating Uveitis

Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma

Nov 01 2016 // Raven ML, Krivochenitser RI, Lucarelli MJ. Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma. Ophthalmology. 2016 Nov;123(11):2385. PMID: 27772650 Read More

Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma

Scleritis with Devastating Consequences

Nov 01 2016 // Raven ML, Burris CK, Potter HD. Scleritis with Devastating Consequences. Ophthalmology. 2016 Nov;123(11):2337. PMID: 27772649. Read More

Scleritis with Devastating Consequences

Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma

Nov 01 2016 // Raven ML, Krivochenitser RI, Lucarelli MJ. Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma. Ophthalmology. 2016 Nov;123(11):2385. PMID: 27772650 Read More

Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma

Merkel Cell Carcinoma of the Eyelid

Oct 31 2016 // Raven ML, Selid PD, Lucarelli MJ. Merkel Cell Carcinoma of the Eyelid. Ophthalmology. 2016 Oct 31;123(10):2126. PMID: 27664912. Read More

Merkel Cell Carcinoma of the Eyelid

The role of acetoacetate in Amadori product formation of human serum albumin

Oct 31 2016 // Bohlooli M, Ghaffari-Moghaddam M, Khajeh M, Shahraki-Fallah G, Haghighi-Kekhaiye B, Sheibani N. The role of acetoacetate in Amadori product formation of human serum albumin. Journal of Photochemistry and Photobiology B: Biology. 2016 Oct 31; 163:345-51.… Read More

The role of acetoacetate in Amadori product formation of human serum albumin

 CONTACT US

310 N Midvale Blvd, Suite 205
Madison, Wisconsin 53705
Phone: (608) 262-1334
Fax: (608) 265-9509

EMAIL US