PubMed ID: 30998240
Author(s): Gupta MP, Yonekawa Y, Campbell JP, Rusu I, Zahid S, Patel SN, Chau F, Jonas KE, Oltra E, Orlin A, Chang J, Horowitz J, Abramson DH, Marr B, Capone A, Paul Chan RV. Early Diagnosis and Management of Aggressive Posterior Vitreoretinopathy Presenting in Premature Neonates. Ophthalmic Surg Lasers Imaging Retina. 2019 Apr 1;50(4):201-207. doi: 10.3928/23258160-20190401-01. PMID 30998240
Journal: Ophthalmic Surgery, Lasers & Imaging Retina, Volume 50, Issue 4, Apr 2019
BACKGROUND AND OBJECTIVE Aggressive posterior vitreoretinopathy (APVR) manifests with a broad area of retinal avascularity, progressive neovascularization, and/or tractional retinal detachment during the neonatal period.
PATIENTS AND METHODS A multicenter, retrospective, observational, consecutive case series study was performed to evaluate the retinal findings and structural retinal outcomes in patients treated for APVR within the first 3 months of life.
RESULTS Three premature neonates with a non-retinopathy of prematurity (ROP) APVR identified during routine ROP screening exams exhibited relatively severe, rapidly progressive retinal vascular abnormalities. Immediate laser photocoagulation of the avascular retina and vitrectomy for traction retinal detachment within several days to weeks improved or stabilized the retinal anatomy in all cases.
CONCLUSIONS This series describes clinical features in APVR in premature infants and suggests that early diagnosis and intervention may mitigate the typical aggressive course and poor prognosis of this condition. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:201-207.].
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