PubMed ID: 37901895
Author(s): Mansour AM, Lopez-Guajardo L, Belotto S, Lima LH, Charbaji AR, Schwartz SG, Wu L, Smiddy WE, Ascaso J, Jurgens I, Foster RE, Elnahry AG, Sinawat S, Pinilla I, Perez-Salvador Garcia E, Suarez Leoz M, Olivier Pascual N, Zago Ribeiro L, Arroyo Castillo R, Navea A, Kadayifcilar S, Ellabban AA, Rey A, Mansour HA, Tripathy K, Kozak I, Uwaydat SH, Valero MS, Cobo-Soriano R, Diaz-Barreda MD, Monje Fernandez L, Gonzalez Del Valle F, Lopez Liroz I, Vazquez Cruchaga E, Fonollosa A, Esteban Floria O, Relimpio Lopez MI, Shah G, Wingelaar MJ, Ravani R, Donate-Lopez J, Rubio Velazquez E, Parodi M; Collaborative Postsurgical Residual Subretinal Fluid Study Group. Recovery course of persistent posterior subretinal fluid after successful repair of rhegmatogenous retinal detachment. Eur J Ophthalmol. 2024 Jul;34(4):1217-1227. doi: 10.1177/11206721231210693. Epub 2023 Oct 30. PMID 37901895
Journal: European Journal Of Ophthalmology, Volume 34, Issue 4, Jul 2024
PURPOSE To investigate best corrected visual acuity (BCVA), subretinal fluid (SRF) absorption time or ellipsoid zone (EZ) restoration time and various variables in patients with persistent SRF after successful primary repair of rhegmatogenous retinal detachment (RRD).
METHODS This retrospective multicenter study allowed independent analysis of the healing pattern by two observers based on composite of serial cross-sectional macular optical coherence tomography (OCT) scans. Univariate and multivariate analyses were implemented.
RESULTS One hundred and three cases had persistent SRF after pars plana vitrectomy, scleral buckling, or pneumatic retinopexy. By univariate analysis, SRF resolution time correlated positively with the number of retinal breaks (p < 0.001) and with increased myopia (p = 0.011). Using multivariate analysis, final BCVA (log MAR) correlated positively with age, duration of RRD, initial BCVA (OR = 3.28; [95%CI = 1.44-7.47]; p = 0.015), and SRF resolution time (OR = 0.46 [95%CI 0.21-1.05]; p = 0.049). EZ restoration time was longer with increasing number of retinal tears (OR = 0.67; [95%CI 0.29-1.52]; p = 0.030), worse final BCVA, and presence of macula-off RRD (OR = 0.26; [95%CI 0.08-0.88]; p = 0.056). SRF resolution time correlated marginally with prone position.
CONCLUSIONS Residual posterior SRF is more common in eyes with multiple breaks or in myopic eyes. Final BCVA is better in younger subjects and in eyes with shorter duration of RRD. Persistent SRF is a self-limited disorder with a mean resolution of 11.2 months with good visual prognosis improving from a mean baseline logMAR of 1.08 to 0.25 at one year.