Granulomatous Uveitis

PubMed ID: 34033343

Author(s): Elnahry AG, Elnahry GA. Granulomatous Uveitis. 2023 Apr 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK570581/ PMID 34033343

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The middle layer of the eye, also known as the uvea (uva or “grape” in Greek), is made up of the iris, the ciliary body, and the choroid. Uveitis is an inflammation of the middle layer of the eye which can involve one, two, or all three parts of the uveal tract. It can be classified in several ways; anatomically into anterior, intermediate, posterior, or panuveitis according to the site of inflammation, etiologically into infectious or non-infectious uveitis according to the underlying cause, and histopathologically into granulomatous or non-granulomatous uveitis according to the immunological response of the body to the cause of uveitis. Because many conditions, both ocular and systemic, may result in uveitis, these classifications are important as they may help in narrowing down the differential diagnosis in a case of uveitis since each condition usually presents a characteristic clinical picture. In this article, we will review the multidisciplinary approach to the diagnosis and management of granulomatous uveitis.