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2024 Kambara Symposium

This annual symposium showcases vision research being conducted on the UW-Madison campus and at other midwestern universities. The 2024 Kambara Vision Sciences Symposium keynote speaker is Budd Tucker, PhD, from the Department of Ophthalmology and Visual Sciences at the University of Iowa Health Care Carver College of Medicine. Each session will begin with one of three invited featured speakers John Fingert, MD, PhD, from the University of Iowa, Gregory Schwartz, PhD, from Northwestern University, and Deepak Shukla, PhD, at University of Illinois Chicago.

Please register to attend:

Kambara Registration

George Kambara, MD, Vision Sciences Symposium
8 AM – 4 PM · Friday, April 12, 2024
Health Sciences Learning Center, Room 1335
750 Highland Avenue
— Complimentary Breakfast at 8 AM —

Keynote Speaker

Budd TuckerBudd Tucker, PhD is the Howard Ruby Chair for Regenerative Ophthalmology, Ophthalmology and Visual Sciences at the University of Iowa’s Carver College of Medicine. He directs the Tucker Stem Cell Laboratory, and his principal research focus is Inherited retinal degenerative diseases such as retinitis pigmentosa (RP), Leber Congenital Amaurosis (LCA), Batten Disease, Usher Syndrome, BBS, and Best disease, collectively a major cause of incurable blindness in the western world. Currently, his lab is involved in the development of two major therapeutic approaches for this class of disease: gene replacement therapy and cell replacement therapy. Dr. Tucker has extensive experience in this area and published several manuscripts and scientific abstracts relating to stem cell production, culture, isolation, differentiation, and transplantation (via both cell injection and polymer scaffold-mediated delivery). Dr. Tucker earned a BAH in Psychology from Sir Wilfred Grenfell College at Memorial University of Newfoundland. He completed his PhD in Neuroscience at the Memorial University of Newfoundland and completed a fellowship in ophthalmology at Schepens Eye Research Institute at the Massachusetts Eye and Ear Infirmary in Harvard Medical School.

Featured Speakers

John FingertJohn H. Fingert, MD, PhD is the Hadley-Carver Chair in Glaucoma, Professor and Director of the Glaucoma Service for the Department of Ophthalmology and Visual Sciences at the University of Iowa’s Carver College of Medicine. He directs the glaucoma genetics lab at the University of Iowa’s Institute for Vision Research and his principal research focus is investigating the genetic basis of glaucoma. Dr. Fingert has made key discoveries including the identification of the first glaucoma-causing gene, myocilin (MYOC), and one of the few known genes for normal tension glaucoma (TBK1). He has also examined the influence of glaucoma risk factor genes on disease with investigations of the participants in the Ocular Hypertension Treatment Study (OHTS). Dr. Fingert has authored over 175 peer-reviewed articles and 10 book chapters. He has also been elected to the Glaucoma Research Society, the American Ophthalmological Society, and the American Society for Clinical Investigation. He currently serves on the scientific advisory boards of The Glaucoma Foundation and Research to Prevent Blindness and is on the editorial boards of the American Journal of Glaucoma, Journal of Glaucoma, and Ophthalmic Genetics.

Gregory SchwartzGregory Schwartz, PhD is the Derrick T. Vail Professor of Ophthalmology in the Weinberg College of Arts and Sciences at Northwestern University. He directs the Schwartz Lab, which focuses on the circuit mechanisms underlying sensory computation. His work uses the mouse retina as a model system because it allows us to stimulate the circuit precisely with its natural input, patterns of light, and record its natural output, the spike trains of retinal ganglion cells. He harnesses the power of genetic manipulations and detailed information about cell types to uncover new circuits and discover their role in visual processing. His methods include electrophysiology, computational modeling, and circuit tracing using a variety of imaging techniques. Dr. Schwartz completed his BA, BS and MS degrees at Brandeis University and a PhD and Princeton University. He completed a postdoctoral fellowship in Neuroscience at Princeton University and a second postdoctoral fellowship in Physiology at the University of Washington.

Shukla DeepakDeepak Shukla, PhD is the Marion H. Schenk Esq. Professor in Ophthalmology for Research of the Aging Eye and Vice Chair for Research at the University of Illinois College of Medicine. He is also the Director of the Ocular Virology Laboratory. Dr. Shukla studies the viral and immunological basis of ocular diseases, herpes simplex virus (HSV) pathogenesis, and the development of new anti-viral agents and vaccines. His research program is supported by the National Institute of Allergies and Infectious Diseases, Research to Prevent Blindness, Inc., and a number of other foundation grants.  Dr. Shukla has an exceptional commitment to graduate and postgraduate education and serves on important educational committees in the College of Medicine. His laboratory has trained over 25 students and pre- and postdoctoral fellows, of whom three are now independent investigators with faculty appointments.  He reviews grants for the NIH, the American Cancer Society, and Midwest Eye Banks. He lends his expertise as a member of the editorial boards for two biomedical journals and serves regularly as an ad hoc and invited reviewer. He earned his PhD in Microbiology and Immunology from the University of Illinois at Chicago and completed a Postdoctoral Research Fellowship in Microbiology and Immunology at Northwestern University.

 

Kambara Registration

Kambara Program Schedule

8:00 AM Complimentary Breakfast
8:20 – 8:30 AM · Chair’s Welcome: Terri Young, MD, MBA
SESSION I | MODERATOR: ABIGAIL JEBARAJ, MD
8:30 – 9:00 AM · Featured Speaker: Deepak Shukla, Ph.D, University of Illinois
From Eye to Brain: Tracing the Pathogenic Mechanisms of HSV-1 in Vision Impairment and Neurological Dysfunction
9:00 – 9:20 AM · Curtis Brandt, PhD, FARVO
Adenovirus as a Cause of Acute Retinal Necrosis: Characterization of Intravitreal Adenovirus Isolates
9:20 – 9:40 AM · Donna Neumann, PhD
Chromatin Insulators Control the Exit from Latency and the Initiation of Reactivation in Neurons Infected with Herpes Simplex Virus 1 (HSV-1)
9:40 – 10:00 AM · Robert Nickells, PhD
Astrogliosis in the Contralateral Retina After Unilateral Optic Nerve Damage is Regulated by PANX1 Channel Activity
10:00 – 10:20 AM · Break
SESSION II | MODERATOR: AMITHA DOMALPALLY, MD, PHD
10:20 – 10:50 AM · Featured Speaker: Gregory Schwartz, PhD, Northwestern University
The Humbling Complexity of Retinal circuits: Multimodal Classification of Amacrine and Ganglion Cells and How They Can Help Us Understand Visual Processing.
10:50 – 11:10 AM · Thomas Saunders, OD
Comparison of GA Measurements between Optos UWF and Heidelberg Standard Field FAF
11:10 – 11:30 AM · Barbara Blodi, MD
Multimodal Assessment of OCT-derived Precursors of Geographic Atrophy due to Age- Related Macular Degeneration
11:30 – 11:50 AM · Rousen “Alex” Xie, PhD
Micromolded Scaffold to Support Bilayered RPE and Photoreceptor
11:50 – 12:10 PM · Raunak Sinha, PhD
Unique Features of Photoreceptor Adaptation in the Primate Fovea
12:10 – 12:30 PM · Ismail Zaitoun, PhD
Choroidal Vasculature and Immune Cells in the Mouse Eye
12:30 – 1:10 PM · Lunch Break
SESSION III | MODERATOR: NADER SHEIBANI, PHD
1:10 – 1:40 PM · Featured Speaker: John Fingert, MD, PhD, University of Iowa Healthcare
Glaucoma genetics – Functional Analyses of Risk Factors for Polygenic Glaucoma
1:40 – 2:00 PM · Matthew Veldman, PhD
Ligands and Receptors Mediating ON Regeneration
2:00 – 2:20 PM · Colleen McDowell, PhD
Nerve Innervation of High and Low Flow Regions of the Trabecular Meshwork and Schlemm’s Canal
2:20 – 2:40 PM · Jennifer Faralli, PhD
Effects of Aging in Human Trabecular Meshwork (HTM) Cells 2:40 – 2:50 PM
2:40 – 2:50 PM · Break
KEYNOTE INTRODUCTION AND PLAQUE PRESENTATION | DAVID GAMM, MD, PHD
2:50 – 3:50 PM · Keynote Speaker: Budd Tucker, PhD, University of Iowa Healthcare
Using Patient Derived Induced Pluripotent Stem Cells to Model and Treat Inherited Retinal Disease
3:50-4:00 PM · Closing Remarks

The Kambara Symposium is supported by the George Kambara Education Fund and the McPherson Eye Research Institute.