Fundus Photograph Reading Center

Leader in Ophthalmic Image Evaluation since 1970

The Fundus Photograph Reading Center (FPRC) was founded on the enduring principles of intellectual honesty, quality, relevance, innovation and staff satisfaction. We are the core imaging lab within the University of Wisconsin – Madison Department of Ophthalmology and Visual Sciences studying diabetic retinopathy, age-related macular degeneration, uveitis and many more.

We serve a wide range of academic institutions, foundations, pharmaceutical companies and biotech firms including the National Eye Institute, National Institute of Diabetes and Digestive Kidney Diseases, Diabetic Retinopathy Clinical Research Network and the Department of Defense.

 

Meet the FPRC Team

Fundus Photograph Reading Center

Barbara A. Blodi

Professor, Medical Director of the Fundus Photograph Reading Center and Clinical Trials Unit

608-263-7290

Fundus Photograph Reading Center
Fundus Photograph Reading Center

Amitha Domalpally

Ophthalmologist; Research Director of the Fundus Photograph Reading Center

Fundus Photograph Reading Center
Fundus Photograph Reading Center

Michael M. Altaweel

Professor; Co-Director of the Fundus Photograph Reading Center

608-263-7290

Fundus Photograph Reading Center
Fundus Photograph Reading Center

Matthew D. Davis

Professor Emeritus; Founder of the Fundus Photograph Reading Center

608-262-1334

Fundus Photograph Reading Center

Heather Baumhauer

Senior Admin Program Specialist

(608) 265-8794

Fundus Photograph Reading Center

Services

For early phase clinical trials, we offer a streamlined approach tailored to the needs of the study and sponsor.

  • Consultation on protocol design
  • Project management
  • Image analysis
  • Certification and regulatory compliance

 

 

Workflow:

  • Consultation on protocol design
  • Defining ocular disease outcomes
  • Study protocol/start-up training
  • On Site/off Site and web based training on imaging protocols
  • Certification of photography equipment and operators
  • Project management
  • Electronic upload of digital images
  • DICOM conversion
  • Inventory tracking
  • Query monitoring
  • Image quality monitoring and reporting
  • Reproducibility reports for evaluation data
  • Collaboration on manuscript preparation
  • Storage and archival of study images

Evaluation Types

  • Diabetic retinopathy
  • Age-related macular degeneration
  • Macular Edema
  • Vein Occlusion
  • Infectious and non-infectious Uveitis
  • Cytomegalovirus retinitis
  • Lens opacities
  • Glaucoma and neurodegenerative diseases
  • Safety studies to monitor toxicity

Image Evaluations

  • Optical Coherence Tomography (quantitative and layer analysis)
  • Fundus autofluorescence (SLO and camera-based)
  • Color fundus photography
  • Fluorescein and ICG angiograms
  • Red reflex, retroillumination and slit lamp lens photographs

Regulatory Compliance

  • Independent Quality Assurance workgroup, reporting directly to the General Manager
  • FPRC Documentation is compliant with ICH (International Conference on Harmonisation) guidelines and global regulatory requirements.
  • FPRC developed software is compliant with 21 CFR Part 11, ICH and other applicable global regulatory requirements.
  • FPRC staff are trained in HIPAA, human subjects and regulatory compliance and follow a detailed set of policies and standard operating procedures (SOPs).
  • Expert FDA hearing support

Imaging

All imaging technicians and equipment participating in any of our studies are required to be certified by the UW-FPRC for each specific study and each specific procedure within that study, prior to submitting study participant images.

ACTIVE GRANTS

COMING SOON

recent publications

Accuracy of Inferred APOE Genotypes for a Range of Genotyping Arrays and Imputation Reference Panels.

Jun 14 2018 // PubMed ID: 29865051 Author(s): Lupton MK, Medland SE, Gordon SD, Goncalves T, MacGregor S, Mackey DA, Young TL, Duffy DL, Visscher PM, Wray NR, Nyholt DR, Bain L, Ferreira MA, Henders AK, Wallace L, Montgomery… Read More

Accuracy of Inferred APOE Genotypes for a Range of Genotyping Arrays and Imputation Reference Panels.

Diagnostic and therapeutic challenges.

Jun 11 2018 // PubMed ID: 19898189 Author(s): Sisk RA, Berrocal AM, Albini TA, Stanciu N, Gottlieb JL, El Rayes E. Diagnostic and therapeutic challenges. Retina. 2009 Nov-Dec;29(10):1538-41. doi: 10.1097/IAE.0b013e3181ba2456. Journal: Retina (Philadelphia, Pa.), Volume 29, Issue 10, Read More

Diagnostic and therapeutic challenges.

High dose zinc increases hospital admissions due to genitourinary complications.

Jun 11 2018 // PubMed ID: 17222649 Author(s): Johnson AR, Munoz A, Gottlieb JL, Jarrard DF. High dose zinc increases hospital admissions due to genitourinary complications. J Urol. 2007 Feb;177(2):639-43. Journal: The Journal Of Urology, Volume 177, Issue 2,… Read More

High dose zinc increases hospital admissions due to genitourinary complications.

Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa.

Jun 11 2018 // PubMed ID: 29881650 Author(s): Strampe MR, Huckenpahler AL, Higgins BP, Tarima S, Visotcky A, Stepien KE, Kay CN, Carroll J. Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa. Transl Vis Sci… Read More

Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa.

An experimental model of preretinal neovascularization in the rabbit.

Jun 11 2018 // PubMed ID: 1987106 Author(s): Antoszyk AN, Gottlieb JL, Casey RC, Hatchell DL, Machemer R. An experimental model of preretinal neovascularization in the rabbit. Invest Ophthalmol Vis Sci. 1991 Jan;32(1):46-52. Journal: Investigative Ophthalmology & Visual Science,… Read More

An experimental model of preretinal neovascularization in the rabbit.

The safety of intravitreal hyaluronidase. A clinical and histologic study.

Jun 11 2018 // PubMed ID: 2242999 Author(s): Gottlieb JL, Antoszyk AN, Hatchell DL, Saloupis P. The safety of intravitreal hyaluronidase. A clinical and histologic study. Invest Ophthalmol Vis Sci. 1990 Nov;31(11):2345-52. Journal: Investigative Ophthalmology & Visual Science, Volume… Read More

The safety of intravitreal hyaluronidase. A clinical and histologic study.

 CONTACT US

310 N. Midvale Blvd, Suite 205
Madison, Wisconsin 53705
Phone: (608) 262-1334
Fax: (608) 265-9509

EMAIL US