Fundus Photograph Reading Center

Leader in Ophthalmic Image Evaluation since 1970

The Fundus Photograph Reading Center (FPRC) was founded on the enduring principles of intellectual honesty, quality, relevance, innovation and staff satisfaction. We are the core imaging lab within the University of Wisconsin – Madison Department of Ophthalmology and Visual Sciences studying diabetic retinopathy, age-related macular degeneration, uveitis and many more.

We serve a wide range of academic institutions, foundations, pharmaceutical companies and biotech firms including the National Eye Institute, National Institute of Diabetes and Digestive Kidney Diseases, Diabetic Retinopathy Clinical Research Network and the Department of Defense.

 

Services

For early phase clinical trials, we offer a streamlined approach tailored to the needs of the study and sponsor.

  • Consultation on protocol design
  • Project management
  • Image analysis
  • Certification and regulatory compliance

 

 

Workflow:

  • Consultation on protocol design
  • Defining ocular disease outcomes
  • Study protocol/start-up training
  • On Site/off Site and web based training on imaging protocols
  • Certification of photography equipment and operators
  • Project management
  • Electronic upload of digital images
  • DICOM conversion
  • Inventory tracking
  • Query monitoring
  • Image quality monitoring and reporting
  • Reproducibility reports for evaluation data
  • Collaboration on manuscript preparation
  • Storage and archival of study images

Evaluation Types

  • Diabetic retinopathy
  • Age-related macular degeneration
  • Macular Edema
  • Vein Occlusion
  • Infectious and non-infectious Uveitis
  • Cytomegalovirus retinitis
  • Lens opacities
  • Glaucoma and neurodegenerative diseases
  • Safety studies to monitor toxicity

Image Evaluations

  • Optical Coherence Tomography (quantitative and layer analysis)
  • Fundus autofluorescence (SLO and camera-based)
  • Color fundus photography
  • Fluorescein and ICG angiograms
  • Red reflex, retroillumination and slit lamp lens photographs

Regulatory Compliance

  • Independent Quality Assurance workgroup, reporting directly to the General Manager
  • FPRC Documentation is compliant with ICH (International Conference on Harmonisation) guidelines and global regulatory requirements.
  • FPRC developed software is compliant with 21 CFR Part 11, ICH and other applicable global regulatory requirements.
  • FPRC staff are trained in HIPAA, human subjects and regulatory compliance and follow a detailed set of policies and standard operating procedures (SOPs).
  • Expert FDA hearing support

Imaging

All imaging technicians and equipment participating in any of our studies are required to be certified by the UW-FPRC for each specific study and each specific procedure within that study, prior to submitting study participant images.

ACTIVE GRANTS

COMING SOON

recent publications and NEWS

Ophthalmology Patient Perceptions of Open Payments Information.

Sep 23 2018 // PubMed ID: 30242324 Author(s): Stein GE, Kamler JJ, Chang JS. Ophthalmology Patient Perceptions of Open Payments Information. JAMA Ophthalmol. 2018 Sep 13. doi: 10.1001/jamaophthalmol.2018.4167. [Epub ahead of print] Journal: Jama Ophthalmology, Sep 2018 Importance Since… Read More

Ophthalmology Patient Perceptions of Open Payments Information.

Association of Cadmium and Lead Exposure With the Incidence of Contrast Sensitivity Impairment Among Middle-aged Adults.

Sep 23 2018 // PubMed ID: 30242333 Author(s): Paulsen AJ, Schubert CR, Johnson LJ, Chen Y, Dalton DS, Klein BEK, Klein R, Pinto A, Cruickshanks KJ. Association of Cadmium and Lead Exposure With the Incidence of Contrast Sensitivity Impairment… Read More

Association of Cadmium and Lead Exposure With the Incidence of Contrast Sensitivity Impairment Among Middle-aged Adults.

Simultaneous assessment of aberrant retinal vascularization, thickness, and function in an in vivo mouse oxygen-induced retinopathy model.

Sep 14 2018 // PubMed ID: 30209267 Author(s): Mezu-Ndubuisi OJ, Adams T, Taylor LK, Nwaba A, Eickhoff J. Simultaneous assessment of aberrant retinal vascularization, thickness, and function in an in vivo mouse oxygen-induced retinopathy model. Eye (Lond). 2018 Sep… Read More

Simultaneous assessment of aberrant retinal vascularization, thickness, and function in an in vivo mouse oxygen-induced retinopathy model.

Refraction and Change in Refraction Over a 20-Year Period in the Beaver Dam Eye Study.

Sep 13 2018 // PubMed ID: 30208419 Author(s): Bomotti S, Lau B, Klein BEK, Lee KE, Klein R, Duggal P, Klein AP. Refraction and Change in Refraction Over a 20-Year Period in the Beaver Dam Eye Study. Invest Ophthalmol… Read More

Refraction and Change in Refraction Over a 20-Year Period in the Beaver Dam Eye Study.

The Functional Benefits of Strabismus Surgery.

Sep 11 2018 // PubMed ID: 30196758 Author(s): Kushner BJ. The Functional Benefits of Strabismus Surgery. J Binocul Vis Ocul Motil. 2018 Apr-Jun;68(2):59-62. doi: 10.1080/2576117X.2018.1460972. Epub 2018 Apr 18. Journal: Journal Of Binocular Vision And Ocular Motility, Volume 68,… Read More

The Functional Benefits of Strabismus Surgery.

Re-Operation Strategies in Strabismus-Cooper’s Dictum Amended.

Sep 11 2018 // PubMed ID: 30196759 Author(s): Kushner BJ. Re-Operation Strategies in Strabismus-Cooper’s Dictum Amended. J Binocul Vis Ocul Motil. 2018 Apr-Jun;68(2):45-53. doi: 10.1080/2576117X.2018.1460181. Epub 2018 Apr 11. Journal: Journal Of Binocular Vision And Ocular Motility, Volume 68,… Read More

Re-Operation Strategies in Strabismus-Cooper’s Dictum Amended.

 CONTACT US

310 N. Midvale Blvd, Suite 205
Madison, Wisconsin 53705
Phone: (608) 262-1334
Fax: (608) 265-9509

EMAIL US