Fundus Photograph Reading Center

Leader in Ophthalmic Image Evaluation since 1970

We are the core imaging lab within the University of Wisconsin – Madison Department of Ophthalmology and Visual Sciences studying diabetic retinopathy, age-related macular degeneration, uveitis and other ophthalmic diseases.The Fundus Photograph Reading Center (FPRC) was founded on the enduring principles of intellectual honesty, quality, relevance, innovation and staff satisfaction.

We serve a wide range of academic institutions, foundations, pharmaceutical companies and biotech firms including the National Eye Institute, National Institute of Diabetes and Digestive Kidney Diseases, Diabetic Retinopathy Clinical Research Network and the Department of Defense.

 

Services

For early phase clinical trials, we offer a streamlined approach tailored to the needs of the study and sponsor.

  • Consultation on protocol design
  • Project management
  • Image analysis
  • Certification and regulatory compliance

 

 

Workflow:

  • Consultation on protocol design
  • Defining ocular disease outcomes
  • Study protocol/start-up training
  • On Site/off Site and web based training on imaging protocols
  • Certification of photography equipment and operators
  • Project management
  • Electronic upload of digital images
  • DICOM conversion
  • Inventory tracking
  • Query monitoring
  • Image quality monitoring and reporting
  • Reproducibility reports for evaluation data
  • Collaboration on manuscript preparation
  • Storage and archival of study images

Evaluation Types

  • Diabetic retinopathy
  • Age-related macular degeneration
  • Macular Edema
  • Vein Occlusion
  • Infectious and non-infectious Uveitis
  • Cytomegalovirus retinitis
  • Lens opacities
  • Glaucoma and neurodegenerative diseases
  • Safety studies to monitor toxicity

Image Evaluations

  • Optical Coherence Tomography (quantitative and layer analysis)
  • Fundus autofluorescence (SLO and camera-based)
  • Color fundus photography
  • Fluorescein and ICG angiograms
  • Red reflex, retroillumination and slit lamp lens photographs

Regulatory Compliance

  • Independent Quality Assurance workgroup, reporting directly to the General Manager
  • FPRC Documentation is compliant with ICH (International Conference on Harmonisation) guidelines and global regulatory requirements.
  • FPRC developed software is compliant with 21 CFR Part 11, ICH and other applicable global regulatory requirements.
  • FPRC staff are trained in HIPAA, human subjects and regulatory compliance and follow a detailed set of policies and standard operating procedures (SOPs).
  • Expert FDA hearing support

Imaging

All imaging technicians and equipment participating in any of our studies are required to be certified by the UW-FPRC for each specific study and each specific procedure within that study, prior to submitting study participant images.

ACTIVE GRANTS

COMING SOON

recent publications and NEWS

2019 Distinguished Alumnus Announced

Sep 04 2019 // Dr. Andy Harris Honored as 2019 OAA Distinguished Alumni Award Recipient This year’s Distinguished Alumni Award recipient, W. Andy Harris, MD (Residency 1974), recalled his time at the University of Wisconsin Department of Ophthalmology and… Read More

2019 Distinguished Alumnus Announced

Cadmium, obesity, and education, and the 10-year incidence of hearing impairment: The beaver dam offspring study.

Aug 20 2019 // PubMed ID: 31424564 Author(s): Dalton DS, Schubert CR, Pinto A, Fischer ME, Huang GH, Klein BEK, Klein R, Pankow JS, Paulsen AJ, Tsai MY, Tweed TS, Cruickshanks KJ. Cadmium, obesity, and education, and the 10-year… Read More

Cadmium, obesity, and education, and the 10-year incidence of hearing impairment: The beaver dam offspring study.

Tunicamycin-induced photoreceptor atrophy precedes degeneration of retinal capillaries with minimal effects on retinal ganglion and pigment epithelium cells.

Aug 20 2019 // PubMed ID: 31421136 Author(s): Wang S, Liu Y, Tan JW, Hu T, Zhang HF, Sorenson CM, Smith JA, Sheibani N. Tunicamycin-induced photoreceptor atrophy precedes degeneration of retinal capillaries with minimal effects on retinal ganglion and… Read More

Tunicamycin-induced photoreceptor atrophy precedes degeneration of retinal capillaries with minimal effects on retinal ganglion and pigment epithelium cells.

Associations of Hearing Sensitivity, Higher-order Auditory Processing, and Cognition over Time in Middle-aged Adults.

Aug 17 2019 // PubMed ID: 31418812 Author(s): Merten N, Fischer ME, Tweed TS, Breteler MMB, Cruickshanks KJ. Associations of Hearing Sensitivity, Higher-order Auditory Processing, and Cognition over Time in Middle-aged Adults. J Gerontol A Biol Sci Med Sci.… Read More

Associations of Hearing Sensitivity, Higher-order Auditory Processing, and Cognition over Time in Middle-aged Adults.

Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.

Aug 16 2019 // PubMed ID: 31415580 Author(s): Wong YL, Hysi P, Cheung G, Tedja M, Hoang QV, Tompson SWJ, Whisenhunt KN, Verhoeven V, Zhao W, Hess M, Wong CW, Kifley A, Hosoda Y, Haarman AEG, Hopf S, Laspas… Read More

Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.

RISK FACTORS FOR HEARING IMPAIRMENT IN TYPE 1 DIABETES.

Aug 15 2019 // PubMed ID: 31412233 Author(s): Braffett BH, Lorenzi GM, Cowie CC, Gao X, Bainbridge KE, Cruickshanks KJ, Kramer JR, Gubitosi-Klug RA, Larkin ME, Barnie A, Lachin JM, Schade DS; DCCT/EDIC Research Group. RISK FACTORS FOR HEARING… Read More

RISK FACTORS FOR HEARING IMPAIRMENT IN TYPE 1 DIABETES.

 CONTACT US

310 N. Midvale Blvd, Suite 205
Madison, Wisconsin 53705
Phone: (608) 262-1334
Fax: (608) 265-9509

EMAIL US