Fundus Photograph Reading Center

Leader in Ophthalmic Image Evaluation since 1970

We are the core imaging lab within the University of Wisconsin – Madison Department of Ophthalmology and Visual Sciences studying diabetic retinopathy, age-related macular degeneration, uveitis and other ophthalmic diseases.The Fundus Photograph Reading Center (FPRC) was founded on the enduring principles of intellectual honesty, quality, relevance, innovation and staff satisfaction.

We serve a wide range of academic institutions, foundations, pharmaceutical companies and biotech firms including the National Eye Institute, National Institute of Diabetes and Digestive Kidney Diseases, Diabetic Retinopathy Clinical Research Network and the Department of Defense.

 

Services

For early phase clinical trials, we offer a streamlined approach tailored to the needs of the study and sponsor.

  • Consultation on protocol design
  • Project management
  • Image analysis
  • Certification and regulatory compliance

 

 

Workflow:

  • Consultation on protocol design
  • Defining ocular disease outcomes
  • Study protocol/start-up training
  • On Site/off Site and web based training on imaging protocols
  • Certification of photography equipment and operators
  • Project management
  • Electronic upload of digital images
  • DICOM conversion
  • Inventory tracking
  • Query monitoring
  • Image quality monitoring and reporting
  • Reproducibility reports for evaluation data
  • Collaboration on manuscript preparation
  • Storage and archival of study images

Evaluation Types

  • Diabetic retinopathy
  • Age-related macular degeneration
  • Macular Edema
  • Vein Occlusion
  • Infectious and non-infectious Uveitis
  • Cytomegalovirus retinitis
  • Lens opacities
  • Glaucoma and neurodegenerative diseases
  • Safety studies to monitor toxicity

Image Evaluations

  • Optical Coherence Tomography (quantitative and layer analysis)
  • Fundus autofluorescence (SLO and camera-based)
  • Color fundus photography
  • Fluorescein and ICG angiograms
  • Red reflex, retroillumination and slit lamp lens photographs

Regulatory Compliance

  • Independent Quality Assurance workgroup, reporting directly to the General Manager
  • FPRC Documentation is compliant with ICH (International Conference on Harmonisation) guidelines and global regulatory requirements.
  • FPRC developed software is compliant with 21 CFR Part 11, ICH and other applicable global regulatory requirements.
  • FPRC staff are trained in HIPAA, human subjects and regulatory compliance and follow a detailed set of policies and standard operating procedures (SOPs).
  • Expert FDA hearing support

Imaging

All imaging technicians and equipment participating in any of our studies are required to be certified by the UW-FPRC for each specific study and each specific procedure within that study, prior to submitting study participant images.

ACTIVE GRANTS

COMING SOON

recent publications and NEWS

Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.

May 19 2019 // PubMed ID: 31101854 Author(s): Journal: Laboratory Investigation; A Journal Of Technical Methods And Pathology, May 2019 Diabetic retinopathy is the most common microvascular complication of diabetes and is a major cause of blindness, but an… Read More

Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.

In-utero epigenetic factors are associated with early-onset myopia in young children.

May 18 2019 // PubMed ID: 31100065 Author(s): Seow WJ, Ngo CS, Pan H, Barathi VA, Tompson SW, Whisenhunt KN, Vithana E, Chong YS, Juo SH, Hysi P, Young TL, Karnani N, Saw SM. In-utero epigenetic factors are associated… Read More

In-utero epigenetic factors are associated with early-onset myopia in young children.

Getting in on the Action: Live Description at the Theater

May 13 2019 // Visually impaired theater-goers have a new way to experience the art form. A recent article by the Wisconsin State Journal highlights the addition of live audio description at select performances at the Overture Center in Madison. Kelly Warren… Read More

Getting in on the Action: Live Description at the Theater

The Role of Fgf9 In The Production of Neural Retina And Rpe In A Pluripotent Stem Cell Model of Early Human Retinal Development.

May 13 2019 // PubMed ID: 31078532 Author(s): Gamm DM, Clark E, Capowski EE, Singh R. The Role of Fgf9 In The Production of Neural Retina And Rpe In A Pluripotent Stem Cell Model of Early Human Retinal Development.… Read More

The Role of Fgf9 In The Production of Neural Retina And Rpe In A Pluripotent Stem Cell Model of Early Human Retinal Development.

May 06 2019 // PubMed ID: 31056257 Author(s): Journal: Read More

Dietary Antioxidants, Macular Pigment, and Glaucomatous Neurodegeneration: A Review of the Evidence.

May 06 2019 // PubMed ID: 31052471 Author(s): Lawler T, Liu Y, Christensen K, Vajaranant TS, Mares J. Dietary Antioxidants, Macular Pigment, and Glaucomatous Neurodegeneration: A Review of the Evidence. Nutrients. 2019 May 1;11(5). pii: E1002. doi: 10.3390/nu11051002. Review.… Read More

Dietary Antioxidants, Macular Pigment, and Glaucomatous Neurodegeneration: A Review of the Evidence.

 CONTACT US

310 N. Midvale Blvd, Suite 205
Madison, Wisconsin 53705
Phone: (608) 262-1334
Fax: (608) 265-9509

EMAIL US