Researchers at UW–Madison have engineered silicone nanoparticles to cross the blood-brain barrier in mice to deliver brain-wide gene editing therapy for Alzheimer’s disease.
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UW Faculty Present at 2023 AUPO Annual Meeting
University of Wisconsin Department of Ophthalmology and Visual Sciences faculty members and staff will present at the 2023 Association of University Professors of Ophthalmology (AUPO) Annual Meeting in San Diego, CA January 24 – 28, …
Remembering Thomas Stevens, MD: 1938 – 2022
The Department of Ophthalmology and Visual Sciences is saddened by the loss of longtime professor and beloved department leader, Thomas Stevens, MD. Stevens died December 26, 2022, at the age of 84.
Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells.
PubMed ID: 36672270 Author(s): Song YS, Jamali N, Sorenson CM, Sheibani N. Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells. Cells. 2023 Jan 16;12(2):335. doi: 10.3390/cells12020335. PMID 36672270 Journal: …
Clinical Trial Offers Hope to Patients with Dry Age-Related Macular Degeneration
A current clinical trial could lead to approval of a first-ever treatment option for patients with geographic atrophy (GA) secondary to age-related macular degeneration, a progressive, irreversible, and devastating eye disease.
Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures.
PubMed ID: 36598946 Author(s): Ludwig AL, Mayerl SJ, Gao Y, Banghart M, Bacig C, Fernandez Zepeda MA, Zhao X, Gamm DM. Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures. Proc Natl …
Lab-Grown Retinal Eye Cells Open Door For Clinical Trials to Treat Blindness
Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a “handshake” that may show the cells are ready for trials in humans with degenerative eye disorders.
Inflammation, metabolic dysregulation and environmental neurotoxins and risk of cognitive decline and impairment in midlife.
PubMed ID: 36114981 Author(s): Schubert CR, Fischer ME, Pinto AA, Paulsen AJ, Chen Y, Huang GH, Klein BEK, Tsai MY, Merten N, Cruickshanks KJ. Inflammation, metabolic dysregulation and environmental neurotoxins and risk of cognitive decline …
The Relative Importance of Hospital Discharge and Patient Composition in Changing Post-Acute Care Utilization and Outcomes Among Medicare Beneficiaries.
PubMed ID: 37077324 Author(s): Cao YJ, Wang Y, Mullahy J, Burns M, Liu Y, Smith M. The Relative Importance of Hospital Discharge and Patient Composition in Changing Post-Acute Care Utilization and Outcomes Among Medicare Beneficiaries. …