Metastasis in a rabbit choroidal melanoma model.

Daniel Albert // Publications // Jan 01 1982

PubMed ID: 7056617

Author(s): Liu LH, Albert DM, Dohlman HG, Chuo N. Metastasis in a rabbit choroidal melanoma model. Invest Ophthalmol Vis Sci. 1982 Jan;22(1):115-8. PMID 7056617

Journal: Investigative Ophthalmology & Visual Science, Volume 22, Issue 1, Jan 1982

A substrain of Greene hamster melanoma adapted to grow in the choroid of the rabbit eye is shown to have the tendency to metastasize. Twenty-one normal rabbits were studied for the effects of vascular inoculation of a tumor cell suspension prepared from this choroidal melanoma, and two rabbits were used for long-term observation of the natural untreated course of the choroidal melanoma. In both groups, metastases to the liver, lung, kidney, and other organs were demonstrated.