Loss of retinal X-cells in cats with neonatal or adult visual cortex damage.

Publications // Ronald Kalil // Jul 02 1982

PubMed ID: 7089543

Author(s): Tong L, Spear PD, Kalil RE, Callahan EC. Loss of retinal X-cells in cats with neonatal or adult visual cortex damage. Science. 1982 Jul 2;217(4554):72-5. PMID 7089543

Journal: Science (New York, N.Y.), Volume 217, Issue 4554, Jul 1982

Recordings were made from single retinal ganglion cell somas in cats whose visual cortical areas 17 and 18 were damaged on the day of birth or in adulthood. Neonatal lesions produced a 78 percent loss of X-cells in the retina, while lesions made in adulthood produced a 22 percent loss. Y-cells and W-cells were unaffected. This retinal abnormality needs to be considered when interpreting studies of behavioral deficits and neural mechanisms of recovery after damage to the visual cortex.