Author(s): Wallow IH, Stevens TS, Greaser ML, Bindley C, Wilson R. Actin filaments in contracting preretinal membranes. Arch Ophthalmol. 1984 Sep;102(9):1370-5.
Journal: Archives Of Ophthalmology (Chicago, Ill. : 1960), Volume 102, Issue 9, Sep 1984
In 14 patients, preretinal membranes, causing retinal traction and severe visual impairment, were removed by vitrectomy and evaluated by light and electron microscopy using myosin subfragment-1 to stain actin filaments. Eight membranes were of vascular origin, six of nonvascular origin. All but one contained bundles of oriented actin filaments within a number of their nonvascular stroma cells, suggesting that the contractile protein action may have been involved in their clinically observed contraction.