Author(s): Massicotte SJ, Hersh PS, Dickersin GR, Craft JL, Albert DM. Olfactory neuroblastoma metastatic to the eye. Graefes Arch Clin Exp Ophthalmol. 1987;225(4):285-90. PMID 3653724
Journal: Graefe’s Archive For Clinical And Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie, Volume 225, Issue 4, 1987
A case of olfactory neuroblastoma metastatic to the choroid is reported and described. Histologically, the tumor consisted of islands of small round cells, many of them surrounding blood vessels in a ‘pseudorosette’ pattern. Numerous mitotic figures were present. Transmission electron microscopy reveals neuritic processes containing neurosecretory granules and microtubules, features characteristic of olfactory neuroblastoma. This is the first published case of an olfactory neuroblastoma demonstrating intraocular metastasis.