Microvascular changes in experimental branch retinal vein occlusion.

Publications // Ronald Danis // Oct 01 1987

PubMed ID: 3120073

Author(s): Danis RP, Wallow IH. Microvascular changes in experimental branch retinal vein occlusion. Ophthalmology. 1987 Oct;94(10):1213-21. PMID 3120073

Journal: Ophthalmology, Volume 94, Issue 10, Oct 1987

Collateral vessel maturation and regional capillary nonperfusion were examined clinically and histopathologically up to 48 months after branch retinal vein occlusion (BVO) in a monkey model. Significant increases in endothelial density, but not pericyte density, were noted in both dilated and normal capillary caliber vessels in regions of collateral flow, independent of duration of BVO from 4 to 15 1/2 months. Patent capillaries in regions of hypoperfusion showed increased endothelial densities but decreased pericyte densities. Pericyte loss was independent of duration of BVO; however, endothelial density may normalize years after BVO in these vessels.