Author(s):Perkins TW, Root TW, Lightfoot EN. Measuring column void volumes with NMR. Anal Chem. 1997 Aug 15;69(16):3293-8.
Journal: Analytical Chemistry, Volume 69, Issue 16, Aug 1997
A novel method for measuring resin porosities and column void volumes with fluorine. NMR has not been developed. In situ measurements of the void volumes accessible to an array of fluorinated probe molecules are used to characterize the pore size distribution of the media. Application of this simple procedure is demonstrated for a commercially packed column and several bulk resins. The porosity distributions obtained by this technique are similar to those obtained by size exclusion chromatography. Unlike chromatographic tracer studies, however, this method does not require packed columns.