PubMed ID: 15990615
Author(s): Rasmussen CA, Kaufman PL. Primate glaucoma models. J Glaucoma. 2005 Aug;14(4):311-4. Review. PMID 15990615
Journal: Journal Of Glaucoma, Volume 14, Issue 4, Aug 2005
The monkey model of ocular hypertension (OHT) with its resultant optic neuropathy closely reflects the optic neurodegeneration associated with human glaucoma. Utilization of the experimental glaucoma model (ExpG) in non-human primates (NHP) has led to advances in the understanding of aqueous humor dynamics, glaucomatous changes in the visual pathways from photoreceptors to the visual cortex, and anterior and posterior ocular segment pharmacological effects.