Age-related macular degeneration and optic disk cupping: the Beaver Dam Eye Study.

Kleins Lab // Publications // Mar 01 2006

PubMed ID: 16490495

Author(s): Hall ER, Klein BE, Knudtson MD, Meuer SM, Klein R. age-related macular degeneration and optic disk cupping: the Beaver Dam Eye Study. Am J Ophthalmol. 2006 Mar;141(3):494-7. PMID 16490495

Journal: American Journal Of Ophthalmology, Volume 141, Issue 3, Mar 2006

PURPOSE To examine the association between presence, severity, and extent of lesions of age-related macular degeneration (AMD) and optic disk and cup diameters in a general population.

DESIGN Cross-sectional study.

METHODS setting: Population-based. study population: Adults aged 43 to 86 years participating in the Beaver Dam Eye Study. observation procedures: Fundus photographs were graded for lesions of AMD using standard protocols. The photographs were obtained during the baseline examination of the Beaver Dam Eye Study. main outcome measure: Optic disk cupping as related to presence, severity, and extent of lesions of AMD.

RESULTS There were no significant differences in the vertical optic disk and cup measurements or in the vertical cup to disk ratios by severity of lesions of AMD (P values all greater than .10). In those eyes with late lesions of AMD, there was no association of the size of the lesions or their distribution in the fundus and the extent of cupping.

CONCLUSIONS From a population perspective, there is no relationship of the presence or severity of AMD and optic disk cupping.