Refraction in adults with diabetes.

Kleins Lab // Publications // Jan 01 2011

PubMed ID: 21220629

Author(s): Klein BE, Lee KE, Klein R. Refraction in adults with diabetes. Arch Ophthalmol. 2011 Jan;129(1):56-62. doi: 10.1001/archophthalmol.2010.322. PMID 21220629

Journal: Archives Of Ophthalmology (Chicago, Ill. : 1960), Volume 129, Issue 1, Jan 2011

OBJECTIVES To examine refraction, change in refraction, and risk factors for change in refraction in adults with type 1 and type 2 diabetes mellitus.

METHODS Population-based study. Modified Early Treatment of Diabetic Retinopathy Study refractions and a standard history were obtained for all participants. Baseline and 10-year follow-up data were available.

RESULTS Age and education were significantly associated with refraction in persons with younger-onset diabetes (T1D) and in those with older-onset diabetes (T2D); refractions were similar for both groups. Persons of similar age with T1D were likely to be more myopic than were those with T2D (P < .01). In those with T1D, on average, there was a -0.28-diopter (D) change in refraction in 10 years. Those with longer duration of diabetes and proliferative retinopathy were more likely to have hyperopic shifts in refraction. In persons with T2D, there was, on average, a +0.48-D change in refraction during the 10 years, but there was little consistency in the amount of change by age at baseline.

CONCLUSIONS In persons of similar age, those with T1D were likely to be slightly more myopic than were those with T2D. Overall, mean refraction and the important risk factors of age and education were similar to those reported in nondiabetic populations.