Author(s):Warner EJ,Chen Y. Reversal of severe visual loss from syphilitic chorioretinitis following penicillin treatment. Neuroophthalmology. 2015 Nov 9;39(6):263-265. eCollection 2015 Dec. PMID 27928366
A 51-year-old Caucasian male was referred to neuro-ophthalmology clinic for an evaluation of acute onset of painless visual loss in the left eye. The ocular examination revealed subtle retinal changes suspicious for chorioretinitis. Laboratory workup revealed a reactive Treponema pallidum particle agglutination assay (TP-PA), confirming the diagnosis of ocular syphilis. The patient was treated with intravenous infusion of penicillin with complete recovery of vision and resolution of retinal abnormalities.