Author(s): Etheridge T, Larson JC, Nork TM,Momont AC. Schwartz-Matsuo syndrome: An important cause of secondary glaucoma. Am J Ophthalmol Case Rep. 2020 Jan 3;17:100586. doi: 10.1016/j.ajoc.2020.100586. eCollection 2020 Mar. PMID 31956728
Journal: American Journal Of Ophthalmology Case Reports, Volume 17, Mar 2020
PURPOSE We report a case of Schwartz-Matsuo syndrome that highlights the pathophysiology, diagnostic challenges, and management considerations of this rare disease.
OBSERVATIONS 31-year-old man with a history of left eye cataract presented with left eye photophobia and elevated intraocular pressure (IOP) of 64 mm Hg. Visual acuity 20/40. Open angles with an increased pigment of trabecular meshwork by gonioscopy, 2 + anterior chamber (AC) cell, superior retinal detachment, and 0.6 cup-to-disc ratio. Electron microscopy of AC fluid demonstrated outer segments of photoreceptors. IOP was lowered with oral and topical ophthalmic antihypertensives. Retinal detachment was treated with pars plana vitrectomy with endolaser, gas tamponade, and AC paracentesis. Follow-up VA 20/20 with normal IOP.
CONCLUSIONS AND IMPORTANCE Schwartz-Matsuo syndrome is characterized by elevated IOP with marked fluctuations, open angles, aqueous cells, and retinal detachment. Diagnosis is supported by electron microscopy of AC fluid with outer segments of photoreceptors. Treatment includes retinal detachment repair and antihypertensive therapy.