Thrombocytopenia and Clear Corneal Incision Cataract Surgery.

Laura Kopplin // Publications // Apr 22 2021

PubMed ID: 33929795

Author(s): Reilly GR, Tipton CW, Armbrust KR, Boyd K, Murray JJ, Kopplin LJ, Berkenstock MK. Thrombocytopenia and Clear Corneal Incision Cataract Surgery. J Cataract Refract Surg. 2021 Apr 22. doi: 10.1097/j.jcrs.0000000000000676. [Epub ahead of print] PMID 33929795

Journal: Journal Of Cataract And Refractive Surgery, Apr 2021

PURPOSE- To investigate complications and outcomes of clear corneal incision cataract surgery in patients with thrombocytopenia.

SETTING- One veterans hospital and two academic medical centers DESIGN-: Multi-center retrospective chart review.

METHODS- All eyes of thrombocytopenic patients that underwent clear corneal incision cataract surgery with a platelet count ≤100 x 10/µl measured ≤30 days prior to surgery were included. Subject demographics, intraoperative complications, use of pupil expansion devices, use of local anesthetic injections, and change in best corrected visual acuity were recorded.

RESULTS- Three sites recorded 40,113 clear corneal incision cataract surgeries, of which 0.49% (196 eyes) were performed on 150 thrombocytopenic patients. The mean platelet count in the study subjects was 73.0×10/µl ± 20.5×10/µl. Two cases of intraoperative iris hemorrhage which were readily controlled occurred in conjunction with pupillary expansion. There were no bleeding complications associated with retrobulbar, peribulbar, or sub-Tenon anesthetic injections. There was a statistically significant improvement (p <0.0001) in visual acuity postoperatively.

CONCLUSION- Clear corneal incision cataract surgery with pupillary expansion devices and local anesthetic injections can be safely performed in patients with thrombocytopenia.