PubMed ID: 34620009
Author(s): Merten N, Pinto AA, Paulsen AJ, Chen Y, Dillard LK, Fischer ME, Ryff CD, Schubert CR, Cruickshanks KJ. The Association of Psychological Well-Being With Sensory and Cognitive Function and Neuronal Health in Aging Adults. J Aging Health. 2022 Aug-Sep;34(4-5):529-538. doi: 10.1177/08982643211046820. Epub 2021 Oct 8. PMID 34620009
Journal: Journal Of Aging And Health, Volume 34, Issue 4 5, 2022
OBJECTIVES Psychological well-being (PWB) may be a potential modifiable risk factor of age-related diseases. We aimed to determine associations of PWB with sensorineural and cognitive function and neuronal health in middle-aged adults.
METHODS This study included 2039 Beaver Dam Offspring Study participants. We assessed PWB, hearing, visual acuity, contrast sensitivity impairment, olfactory impairment, cognition, and retinal (macular ganglion cell inner-plexiform layer, mGCIPL) thickness. Age-sex-education-adjusted multivariable linear, logistic regression, and generalized estimating equation models were used and then further adjusted for health-related confounders.
RESULTS Individuals with higher PWB had better hearing functions, visual acuity, and thicker mGCIPL and reduced odds for hearing, contrast sensitivity and olfactory impairment in age-sex-education-adjusted models. Effects on mGCIPL and visual and olfactory measures decreased with adjustment. Higher PWB was associated with better cognition, better combined sensorineural-cognitive function, and decreased cognitive impairment.
DISCUSSION Psychological well-being was associated with sensorineural-cognitive health indicating a potential of PWB interventions for healthy aging.