PubMed ID: 22524788 Author(s): Nickells RW, Howell GR, Soto I, John SW. Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy. Annu Rev Neurosci. 2012;35:153-79. doi: 10.1146/annurev.neuro.051508.135728. Epub 2012 Apr 12. …
Nickells Lab
A role for epigenetic changes in the development of retinal neurodegenerative conditions.
PubMed ID: 23515137 Author(s): Pelzel HR, Nickells RW. A role for epigenetic changes in the development of retinal neurodegenerative conditions. J Ocul Biol Dis Infor. 2011 Sep;4(3):104-10. doi: 10.1007/s12177-012-9079-9. Epub 2012 Mar 20. PMID 23515137 …
Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor.
PubMed ID: 21541278 Author(s): Mavlyutov TA, Nickells RW, Guo LW. Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor. Mol Vis. 2011 Apr 26;17:1034-43. PMID 21541278 Journal: Molecular Vision, Volume 17, Apr …
The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein.
PubMed ID: 20942963 Author(s): Semaan SJ, Nickells RW. The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein. BMC Cancer. 2010 Oct 13;10:554. doi: 10.1186/1471-2407-10-554. PMID 20942963 …
Variations in the rheostat model of apoptosis: what studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins.
PubMed ID: 20230818 Author(s): Nickells RW. Variations in the rheostat model of apoptosis: what studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins. Exp Eye Res. 2010 Jul;91(1):2-8. …
Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis.
PubMed ID: 20504333 Author(s): Pelzel HR, Schlamp CL, Nickells RW. Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis. BMC Neurosci. 2010 May 26;11:62. doi: 10.1186/1471-2202-11-62. PMID 20504333 Journal: Bmc …
A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death.
PubMed ID: 20360947 Author(s): Semaan SJ, Li Y, Nickells RW. A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death. ASN Neuro. 2010 Mar 31;2(2):e00032. doi: 10.1042/AN20100003. PMID …
Mouse models of retinal ganglion cell death and glaucoma.
PubMed ID: 19105954 Author(s): McKinnon SJ, Schlamp CL, Nickells RW. Mouse models of retinal ganglion cell death and glaucoma. Exp Eye Res. 2009 Apr;88(4):816-24. doi: 10.1016/j.exer.2008.12.002. Epub 2008 Dec 7. Review. PMID 19105954 Journal: Experimental …
Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice.
PubMed ID: 18671875 Author(s): Dietz JA, Li Y, Chung LM, Yandell BS, Schlamp CL, Nickells RW. Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice. BMC Neurosci. 2008 …