BCLXL gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucoma.
Aug 10 2021
PubMed ID: 34376637 Author(s): Donahue RJ, Fehrman RL, Gustafson JR, Nickells RW. BCLX(L) gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucoma. Cell Death Dis. 2021 Aug 10;12(8):781. doi: 10.1038/s41419-021-04068-x. PMID 34376637…
Read MoreIncreased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression.
Aug 02 2021
PubMed ID: 34398198 Author(s): Schmitt HM, Fehrman RL, Maes ME, Yang H, Guo LW, Schlamp CL, Pelzel HR, Nickells RW. Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression. Invest Ophthalmol Vis…
Read MoreThe Influence of Mitochondrial Dynamics and Function on Retinal Ganglion Cell Susceptibility in Optic Nerve Disease.
Jun 25 2021
PubMed ID: 34201955 Author(s): Muench NA, Patel S, Maes ME, Donahue RJ, Ikeda A, Nickells RW. The Influence of Mitochondrial Dynamics and Function on Retinal Ganglion Cell Susceptibility in Optic Nerve Disease. Cells. 2021 Jun…
Read MoreThe effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis.
May 22 2021
PubMed ID: 34022923 Author(s): Grosser JA, Fehrman RL, Keefe D, Redmon M, Nickells RW. The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis. BMC Res Notes. 2021 May 22;14(1):198.…
Read MoreCharacteristics of intracellular propagation of mitochondrial BAX recruitment during apoptosis.
Feb 01 2021
PubMed ID: 33426618 Author(s): Grosser JA, Maes ME, Nickells RW. Characteristics of intracellular propagation of mitochondrial BAX recruitment during apoptosis. Apoptosis. 2021 Feb;26(1-2):132-145. doi: 10.1007/s10495-020-01654-w. Epub 2021 Jan 11. PMID 33426618 Journal: Apoptosis : An…
Read MoreTargeting HDAC3 in the DBA/2J spontaneous mouse model of glaucoma.
Nov 01 2020
PubMed ID: 32971093 Author(s): Schmitt HM, Grosser JA, Schlamp CL, Nickells RW. Targeting HDAC3 in the DBA/2J spontaneous mouse model of glaucoma. Exp Eye Res. 2020 Nov;200:108244. doi: 10.1016/j.exer.2020.108244. Epub 2020 Sep 21. PMID 32971093…
Read MoreBAX-Depleted Retinal Ganglion Cells Survive and Become Quiescent Following Optic Nerve Damage.
Feb 01 2020
PubMed ID: 31673950 Author(s): Donahue RJ, Maes ME, Grosser JA, Nickells RW. BAX-depleted retinal ganglion cells survive and become quiescent following optic nerve damage. Mol Neurobiol. 2020 Feb;57(2):1070-1084. doi: 10.1007/s12035-019-01783-7. Epub 2019 Oct 31. PMID…
Read MoreCompletion of BAX recruitment correlates with mitochondrial fission during apoptosis.
Nov 12 2019
PubMed ID: 31719602 Author(s): Maes ME, Grosser JA, Fehrman RL, Schlamp CL, Nickells RW. Completion of BAX recruitment correlates with mitochondrial fission during apoptosis. Sci Rep. 2019 Nov 12;9(1):16565. doi: 10.1038/s41598-019-53049-w. PMID 31719602 Journal: Scientific…
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Robert Nickells, PhD, Receives Grant Award from BrightFocus Foundation
Apr 30 2018
BrightFocus Foundation Honors Six Vision Researchers Awards New Grants to Study Macular Degeneration and Glaucoma BrightFocus Foundation today recognized six scientists studying macular degeneration and glaucoma, awarding research grants named in honor of leaders…
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