PubMed ID: 31719602 Author(s): Maes ME, Grosser JA, Fehrman RL, Schlamp CL, Nickells RW. Completion of BAX recruitment correlates with mitochondrial fission during apoptosis. Sci Rep. 2019 Nov 12;9(1):16565. doi: 10.1038/s41598-019-53049-w. PMID 31719602 Journal: Scientific …
Nickells Lab
Robert Nickells, PhD, Receives Grant Award from BrightFocus Foundation
BrightFocus Foundation Honors Six Vision Researchers Awards New Grants to Study Macular Degeneration and Glaucoma BrightFocus Foundation today recognized six scientists studying macular degeneration and glaucoma, awarding research grants named in honor of leaders …
Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury.
PubMed ID: 29211617 Author(s): Schmitt HM, Schlamp CL, Nickells RW. Targeting HDAC3 activity with RGFP966 protects against retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury. J Ocul Pharmacol Ther. 2018 Apr;34(3):260-273. doi: …
AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury.
PubMed ID: 29204649 Author(s): Nickells RW, Schmitt HM, Maes ME, Schlamp CL. AAV2-mediated transduction of the mouse retina after optic nerve injury. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6091-6104. doi: 10.1167/iovs.17-22634. PMID 29204649 Journal: Investigative …
Negative regulators of angiogenesis: important targets for treatment of exudative AMD.
PubMed ID: 28679845 Author(s): Farnoodian M, Wang S, Dietz J, Nickells RW, Sorenson CM, Sheibani N. Negative regulators of angiogenesis: important targets for treatment of exudative AMD. Clin Sci (Lond). 2017 Jul 5;131(15):1763-1780. doi: 10.1042/CS20170066. …
Nickells Lab Explores the Molecular Complexities of Retinal Ganglion Cell Death in Glaucoma
January is National Glaucoma Awareness Month Meet Robert Nickells, PhD, a researcher in the University of Wisconsin Department of Ophthalmology and Visual Sciences. Dr. Nickells leads an active research program studying the biology of …
Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system.
PubMed ID: 29386873 Author(s): Donahue RJ, Moller-Trane R, Nickells RW. Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system. Mol Vis. 2017 …
Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis.
PubMed ID: 28880942 Author(s): Maes ME, Schlamp CL, Nickells RW. Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis. PLoS One. 2017 Sep 7;12(9):e0184434. doi: 10.1371/journal.pone.0184434. eCollection 2017. PMID 28880942 Journal: Plo S …
Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells.
PubMed ID: 26733303 Author(s): Schmitt HM, Schlamp CL, Nickells RW. Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells. Neurosci Lett. 2016 Jun 20;625:11-5. doi: 10.1016/j.neulet.2015.12.012. Epub 2015 Dec 28. Review. …