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Young Lab

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.

Posted on October 1, 2010

PubMed ID: 20835239 Author(s): Solouki AM, Verhoeven VJ, van Duijn CM, Verkerk AJ, Ikram MK, Hysi PG, Despriet DD, van Koolwijk LM, Ho L, Ramdas WD, Czudowska M, Kuijpers RW, Amin N, Struchalin M, Aulchenko …

Posted in Publications, Young Lab

Genetic association of insulin-like growth factor-1 polymorphisms with high-grade myopia in an international family cohort.

Posted on September 1, 2010

PubMed ID: 20435602 Author(s): Metlapally R, Ki CS, Li YJ, Tran-Viet KN, Abbott D, Malecaze F, Calvas P, Mackey DA, Rosenberg T, Paget S, Guggenheim JA, Young TL. Genetic association of insulin-like growth factor-1 polymorphisms …

Posted in Publications, Young Lab

Lumican and muscarinic acetylcholine receptor 1 gene polymorphisms associated with high myopia.

Posted on August 1, 2010

PubMed ID: 20414262 Author(s): Guggenheim JA, Zayats T, Hammond C, Young TL. Lumican and muscarinic acetylcholine receptor 1 gene polymorphisms associated with high myopia. Eye (Lond). 2010 Aug;24(8):1411-2; author reply 1412. doi: 10.1038/eye.2010.55. Epub 2010 …

Posted in Publications, Young Lab

Support for TGFB1 as a susceptibility gene for high myopia in individuals of Chinese descent.

Posted on August 1, 2010

PubMed ID: 20697017 Author(s): Khor CC, Fan Q, Goh L, Tan D, Young TL, Li YJ, Seielstad M, Goh DL, Saw SM. Support for TGFB1 as a susceptibility gene for high myopia in individuals of …

Posted in Publications, Young Lab

Family history, near work, outdoor activity, and myopia in Singapore Chinese preschool children.

Posted on August 1, 2010

PubMed ID: 20472747 Author(s): Low W, Dirani M, Gazzard G, Chan YH, Zhou HJ, Selvaraj P, Au Eong KG, Young TL, Mitchell P, Wong TY, Saw SM. Family history, near work, outdoor activity, and myopia …

Posted in Publications, Young Lab

Prevalence of amblyopia and strabismus in young singaporean chinese children.

Posted on July 1, 2010

PubMed ID: 20207979 Author(s): Chia A, Dirani M, Chan YH, Gazzard G, Au Eong KG, Selvaraj P, Ling Y, Quah BL, Young TL, Mitchell P, Varma R, Wong TY, Saw SM. Prevalence of amblyopia and …

Posted in Publications, Young Lab

Genome-wide association identifies ATOH7 as a major gene determining human optic disc size.

Posted on July 1, 2010

PubMed ID: 20395239 Author(s): Macgregor S, Hewitt AW, Hysi PG, Ruddle JB, Medland SE, Henders AK, Gordon SD, Andrew T, McEvoy B, Sanfilippo PG, Carbonaro F, Tah V, Li YJ, Bennett SL, Craig JE, Montgomery …

Posted in Publications, Young Lab

Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.

Posted on May 13, 2010

PubMed ID: 20485516 Author(s): Lu Y, Dimasi DP, Hysi PG, Hewitt AW, Burdon KP, Toh T, Ruddle JB, Li YJ, Mitchell P, Healey PR, Montgomery GW, Hansell N, Spector TD, Martin NG, Young TL, Hammond …

Posted in Publications, Young Lab

Comparative analyses of seven algorithms for copy number variant identification from single nucleotide polymorphism arrays.

Posted on May 1, 2010

PubMed ID: 20142258 Author(s): Dellinger AE, Saw SM, Goh LK, Seielstad M, Young TL, Li YJ. Comparative analyses of seven algorithms for copy number variant identification from single nucleotide polymorphism arrays. Nucleic Acids Res. 2010 …

Posted in Publications, Young Lab
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