PubMed ID: 37615948 Author(s): Young TL. Using Adjustable-Focus Spectacles in Young Children to Meet Increasing Eyecare Needs. JAMA Ophthalmol. 2023 Aug 24. doi: 10.1001/jamaophthalmol.2023.3760. Online ahead of print. No abstract available. PMID 37615948 Journal: Jama …
Young Lab
Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci.
PubMed ID: 37386247 Author(s): Han X, Gharahkhani P, Hamel AR, Ong JS, Renteria ME, Mehta P, Dong X, Pasutto F, Hammond C, Young TL, Hysi P, Lotery AJ, Jorgenson E, Choquet H, Hauser M, Cooke …
Glaucoma Cascade Screening in a High-risk Afro-Caribbean Haitian Population: A Pilot Study.
PubMed ID: 35131981 Author(s): Chang TC, Celestin L, Hodapp EA, Grajewski AL, Junk A, Rothman AL, Duerr ERH, Swaminathan SS, Gedde SJ, Young TL, Wiggs J, Olivier MMG, Quintanilla R, Arrieta E, Savatovsky EJ, Vanner …
Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies.
PubMed ID: 34663817 Author(s): Thomson BR, Liu P, Onay T, Du J, Tompson SW, Misener S, Purohit RR, Young TL, Jin J, Quaggin SE. Cellular crosstalk regulates the aqueous humor outflow pathway and provides new …
Ophthalmic manifestations in Costello syndrome caused by Ras pathway dysregulation during development.
PubMed ID: 34612139 Author(s): Shankar SP, Fallurin R, Watson T, Shankar PR, Young TL, Orel-Bixler D, Rauen KA. Ophthalmic manifestations in Costello syndrome caused by Ras pathway dysregulation during development. Ophthalmic Genet. 2021 Oct 6:1-10. …
Genetic Variants Associated With Human Eye Size Are Distinct From Those Conferring Susceptibility to Myopia.
PubMed ID: 34698770 Author(s): Plotnikov D, Cui J, Clark R, Wedenoja J, Pärssinen O, Tideman JWL, Jonas JB, Wang Y, Rudan I, Young TL, Mackey DA, Terry L, Williams C, Guggenheim JA; UK Biobank Eye …
Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia.
PubMed ID: 33830181 Author(s): Tideman JWL, Pärssinen O, Haarman AEG, Khawaja AP, Wedenoja J, Williams KM, Biino G, Ding X, Kähönen M, Lehtimäki T, Raitakari OT, Cheng CY, Jonas JB, Young TL, Bailey-Wilson JE, Rahi …
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.
PubMed ID: 33627673 Author(s): Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han X, Ong JS, Hewitt AW, Segrè AV, Rouhana JM, Hamel AR, Igo RP Jr, Choquet H, Qassim A, Josyula NS, …
MYOPIA
To identify genes that are involved in eye growth specifically in individuals and families with nearsightedness (myopia).