A Randomized, Partially Masked, Controlled, Phase 2b/3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants with nAMD (ATMOSPHERE)
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UNITY
A Phase 2a, Prospective, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Assess the Safety, Tolerability and Evidence of Activity of a Single Intravitreal Injection of UBX1325 in Patients with Diabetic Macular Edema
PEP
Patient Experience and Preference (PEP) Study in nAMD and DME
Teaming Up for Gene Therapy
*This article originally appeared in the McPherson Eye Research Institute Summer 2021 InSights Newsletter Millions of Americans currently battle inherited visual disorders, armed with very few therapeutic options. Recent advances in genome editing, which many believe …
Visual Acuity Outcome over Time in Non-Infectious Uveitis.
PubMed ID: 31821051 Author(s): Pistilli M, Joffe MM, Gangaputra SS, Pujari SS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Sen HN, Suhler EB, Thorne JE, Bhatt NP, Foster CS, Begum H, Fitzgerald TD, Dreger …
University Station Eye Clinic Expands, Clinics Consolidate
We are delighted to announce that UW Health University Station Eye Clinic has completed renovations on the first and second floors. As part of this plan, two Madison-area clinics will close in the coming weeks, …
Outer Retinal Cell Replacement: Putting the Pieces Together.
PubMed ID: 34724034 Author(s): Ludwig AL, Gamm DM. Outer Retinal Cell Replacement: Putting the Pieces Together. Transl Vis Sci Technol. 2021 Aug 12;10(10):15. doi: 10.1167/tvst.10.10.15. PMID 34724034 Journal: Translational Vision Science & Technology, Volume 10, …
In vivo targeted delivery of nucleic acids and CRISPR genome editors enabled by GSH-responsive silica nanoparticles.
PubMed ID: 34174352 Author(s): Wang Y, Shahi PK, Wang X, Xie R, Zhao Y, Wu M, Roge S, Pattnaik BR, Gong S. In vivo targeted delivery of nucleic acids and CRISPR genome editors enabled by …
BCLXL gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucoma.
PubMed ID: 34376637 Author(s): Donahue RJ, Fehrman RL, Gustafson JR, Nickells RW. BCLX(L) gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucoma. Cell Death Dis. 2021 Aug 10;12(8):781. doi: 10.1038/s41419-021-04068-x. PMID 34376637 …