Serologic and immunopathologic findings in temporal arteritis.

Daniel Albert // Publications // Sep 01 1983

PubMed ID: 6604457

Author(s): Chess J, Albert DM, Bhan AK, Paluck EI, Robinson N, Collins B, Kaynor B. Serologic and immunopathologic findings in temporal arteritis. Am J Ophthalmol. 1983 Sep;96(3):283-9. PMID 6604457

Journal: American Journal Of Ophthalmology, Volume 96, Issue 3, Sep 1983

In 104 patients undergoing biopsies for temporal arteritis, lymphocyte characterization identified both T4 helper/inducer and T8 cytotoxic/suppressor lymphocytes in approximately equal numbers. B lymphocytes were absent. Deposition of IgM and IgG was observed in three of 16 positive biopsy specimens. Antinuclear antibodies were present in ten of 16 biopsy-proven cases of temporal arteritis compared with 19 of 55 in the control group with negative biopsy specimens. Anti-smooth-muscle, anti-DNA, and antimitochondrial antibodies were not useful in distinguishing between the two groups.