Electron microscopy and HLA expression of a new cell line of retinoblastoma.

Daniel Albert // Publications // Apr 01 1987

PubMed ID: 3549617

Author(s): Fournier GA, Sang DN, Albert DM, Craft JL. Electron microscopy and HLA expression of a new cell line of retinoblastoma. Invest Ophthalmol Vis Sci. 1987 Apr;28(4):690-9. PMID 3549617

Journal: Investigative Ophthalmology & Visual Science, Volume 28, Issue 4, Apr 1987

A new continuous retinoblastoma cell line (Rb 355-7) derived from a nonfamilial unilaterally-affected child was studied morphologically and with regard to HLA expression. The tumor was compared with two older and widely studied cell lines, the Y-79 and WERI-Rb1 strains. The Rb 355-7 line grew in tissue culture in clusters and chains. Its doubling time was calculated to be 4.4 days. In contrast to the Y-79 and WERI-Rb1 cell lines, the Rb 355-7 showed a paucity of HLA expression.