Endogenous Pseudallescheria boydii endophthalmitis. Clinicopathologic findings in two cases.

Mark Lucarelli // Publications // Dec 01 1991

PubMed ID: 1841583

Author(s): Pfeifer JD, Grand MG, Thomas MA, Berger AR, Lucarelli MJ, Smith ME. Endogenous Pseudallescheria boydii endophthalmitis. Clinicopathologic findings in two cases. Arch Ophthalmol. 1991 Dec;109(12):1714-7. PMID 1841583

Journal: Archives Of Ophthalmology (Chicago, Ill. : 1960), Volume 109, Issue 12, Dec 1991

Two cases of endogenous Pseudallescheria boydii endophthalmitis are presented. One patient had severe pulmonary fibrosis but no history of ocular trauma and no clinical or laboratory evidence of immunocompromise. Despite therapy with repeated intravitreal miconazole nitrate injections and systemic fluconazole, enucleation of the globe was required, and the patient eventually died with disseminated pseudallescheriasis. The other patient was an immunosuppressed cardiac transplant recipient who also received systemic fluconazole therapy. The infected eye eventually required evisceration, but there was no evidence of disseminated pseudallescheriasis before his death of unrelated causes.