Idiopathic reactive hyperplasia of the retinal pigment epithelium.

Frank Myers // Matthew Davis // Publications // Jan 01 1999

PubMed ID: 9930160

Author(s): Olsen TW, Frayer WC, Myers FL, Davis MD, Albert DM. Idiopathic reactive hyperplasia of the retinal pigment epithelium. Arch Ophthalmol. 1999 Jan;117(1):50-4. PMID 9930160

Journal: Archives Of Ophthalmology (Chicago, Ill. : 1960), Volume 117, Issue 1, Jan 1999

OBJECTIVES To present and discuss 2 patients with acquired peripapillary pigmented lesions.

METHODS We reviewed the patients’ clinical records and histopathologic findings.

RESULTS The first patient was diagnosed with a pigmented papillary lesion that was followed up for 38 years. The second patient was a child with neurofibromatosis type 1 who developed a pigmented peripapillary lesion following excision of an optic nerve glioma. Histologic findings in both cases demonstrated hyperplasia of the retinal pigment epithelium with associated findings.

CONCLUSIONS The lesions presented an idiopathic reactive hyperplasia of the retinal pigment epithelium. The clinical and histopathologic findings resemble findings reported with the combined hamartoma. We suggest that such lesions are reactive in nature, rather than hamartomatous.