Enrofloxacin-induced retinopathy in a guanaco (Lama guanicoe).

Publications // Richard Dubielzig // Dec 01 2006

PubMed ID: 17315443

Author(s): Harrison TM, Dubielzig RR, Harrison TR, McClean M. Enrofloxacin-induced retinopathy in a guanaco (Lama guanicoe). J Zoo Wildl Med. 2006 Dec;37(4):545-8. PMID 17315443

Journal: Journal Of Zoo And Wildlife Medicine : Official Publication Of The American Association Of Zoo Veterinarians, Volume 37, Issue 4, Dec 2006

A 4-yr-old male guanaco (Lama guanicoe) in a multispecies exhibit presented with a laceration in the axillary region. The laceration was surgically repaired. Medical treatment was initiated with penicillin G procaine and benzathine (1920 IU/kg, i.m., s.i.d. for 14 days), and enrofloxacin (2.4 mg/kg, i.m., s.i.d. for 14 days). The animal was later treated with trimethoprim-sulfadiazine (24 mg/kg, p.o., s.i.d. for 10 days). Twenty-six days after initial presentation, the guanaco was suspected to be blind. An ophthalmic examination confirmed retinal damage. On postmortem histological evaluation, there was outer retinal atrophy that was most severe in the central retina with localized foci of complete retinal atrophy; lesions were similar to those observed in enrofloxacin retinal toxicity in cats.