The relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration.

Publications // Ronald Danis // May 01 2007

PubMed ID: 17552388

Author(s): Rechtman E, Harris A, Siesky B, Kagemann L, Danis RP, Sines D, Ciulla TA. The relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging. 2007 May-Jun;38(3):219-25. doi: 10.3928/15428877-20070501-06. PMID 17552388

Journal: Ophthalmic Surgery, Lasers & Imaging : The Official Journal Of The International Society For Imaging In The Eye, Volume 38, Issue 3,

BACKGROUND AND OBJECTIVE To evaluate the relationship between retrobulbar and choroidal hemodynamics in non-neovascular age-related macular degeneration.

PATIENTS AND METHODS Thirteen patients with age-related macular degeneration were assessed by both color Doppler imaging and scanning laser ophthalmoscope indocyanine green (ICG) angiography. Color Doppler imaging was used to measure peak systolic and end diastolic velocity (from which the resistance index, a measure of the resistance to flow downstream, was calculated) in the retrobulbar vessels. Scanning laser ophthalmoscope ICG angiograms were analyzed by area dilution analysis for quantitative choroidal fluorescence intensity assessment. Color Doppler imaging parameters were correlated with scanning laser ophthalmoscope ICG area dilution analysis parameters.

RESULTS A good correlation was found between the posterior ciliary arteries resistance index and scanning laser ophthalmoscope ICG area dilution analysis fluorescence duration.

CONCLUSIONS Scanning laser ophthalmoscope ICG area dilution analysis “duration” may serve as an alternative to color Doppler imaging in assessing the resistance to blood flow in the posterior ciliary arteries.