Multiple ophthalmic abnormalities in an infant rhesus macaque (Macaca mulatta).

Publications // Richard Dubielzig // Feb 01 2008

PubMed ID: 18269523

Author(s): Ribka EP, Dubielzig RR. Multiple ophthalmic abnormalities in an infant rhesus macaque (Macaca mulatta). J Med Primatol. 2008 Feb;37 Suppl 1:16-9. doi: 10.1111/j.1600-0684.2007.00263.x. PMID 18269523

Journal: Journal Of Medical Primatology, Volume 37 Suppl 1, Feb 2008

BACKGROUND A 4.5-month-old male colony-bred Indian rhesus macaque was presented for presumed trauma to the right eye. The globe was centrally distended 5 mm, with apparent hyphema and moderate to severe corneal edema. Surgical enucleation was performed. The initial histopathology report concluded chronic keratitis. Nearly 3 years later, a diagnosis of goniodysgenesis was made. The eye was sent to a veterinary ocular pathologist for definitive diagnosis.

CONCLUSIONS Final conclusions were anterior segment and corneal defects. Based on the retinal pathology and optic nerve pathology, there was evidence of optic nerve atrophy, a recently described condition in macaques.