Functional properties of fibronectin in the trabecular meshwork.

Donna Peters // Publications // Apr 01 2009

PubMed ID: 18835267

Author(s): Faralli JA, Schwinn MK, Gonzalez JM Jr, Filla MS, Peters DM. Functional properties of fibronectin in the trabecular meshwork. Exp Eye Res. 2009 Apr;88(4):689-93. doi: 10.1016/j.exer.2008.08.019. Epub 2008 Sep 18. Review. PMID 18835267

Journal: Experimental Eye Research, Volume 88, Issue 4, Apr 2009

Fibronectin plays a number of important roles in the extracellular matrix (ECM) including providing structural support and signaling cues for cell survival, migration, differentiation, gene expression, growth factor signaling, and cell contractility. In this review, we examine recent findings about the biological and structural properties of fibronectin and discuss how these properties could contribute to the regulation of aqueous humor (AH) outflow in the trabecular meshwork (TM).