Author(s): Detty SQ, Peebles JK, Guerrieri JM, Seroogy CM, Struck MC, Arkin LM, Henderson SL. Vaccine-strain Herpes zoster ophthalmicus in a 14-month-old boy prompting an immunodeficiency workup: case report and review of vaccine-strain Herpes zoster. Pediatr Infect Dis J. 2020 Feb;39(2):e25-e27. doi: 10.1097/INF.0000000000002545. PMID 31929435
We present a case of herpes zoster ophthalmicus in an otherwise healthy 14-month-old male associated with vaccine-strain varicella-zoster virus 11 weeks after monovalent varicella vaccine administration. Herpes zoster ophthalmicus, especially in the setting of familial immunoglobulin A deficiency, prompted further immunologic workup. A high index of suspicion is necessary for timely diagnosis and treatment of vaccine-strain herpes zoster.