Molecular Genetics of Myopia

  • Sponsor: National Institutes of Health
  • Principal Investigator: Terri Young, MD, MBA, FARVO
  • Study Coordinator: Nickie Stangel

Study objective:

To identify genes that are involved in eye growth specifically in individuals and families with nearsightedness (myopia).

Study design:

One study visit involving a medical history questionnaire, ophthalmic evaluations, and a blood/saliva sample for genetic/DNA analysis.

Inclusion criteria:

  • Male or female patients ≥ 13 years of age
  • Diagnosis of myopia of -5.00 Diopters or greater
  • History of myopia prior to age 12 years
  • History of myopia prior to refractive surgery or cataract extraction
  • No history of a childhood eye disorder that may predispose to myopia
  • Weight ˃ 1250 grams (~2.8 lbs) at birth

Exclusion criteria:

  • History of childhood eye disorder that my predispose to myopia, such as congenital glaucoma, visual form deprivation (retinal hemorrhage, congenital cataract, corneal opacification), retinopathy of prematurity, history of prematurity, retinal dystrophy, etc.
  • Any evidence of syndromic myopia (Stickler, Ehler-Danlos, Down, or Marfan syndromes, etc.)

Contact Nickie Stangel with questions, 608-263-8783