PubMed ID: 35446819
Author(s): Richards PJ, Kulkarni AD, Nork TM, Leys M, Hinkle D, Conlin KA, Chang S, Chang JS. NONSURGICAL RESOLUTION OF FULL-THICKNESS MACULAR HOLES WITHOUT VITREOMACULAR TRACTION. Retin Cases Brief Rep. 2023 Sep 1;17(5):584-587. doi: 10.1097/ICB.0000000000001249. PMID 35446819
Journal: Retinal Cases & Brief Reports, Volume 17, Issue 5, Sep 2023
BACKGROUND/PURPOSE The purpose of this study was to report a case series of full-thickness macular holes without vitreomacular traction that resolved without surgery.
METHODS This study is a retrospective case series of 11 patients who demonstrated closure of full-thickness macular holes without surgical intervention.
RESULTS All full-thickness macular holes closed, with all patients having improvement in visual acuity. All but one of the cases had visual acuity better than 20/40 at last recorded visit. Most cases presented with associated epiretinal membrane (73%), cystoid changes (64%), defects <150 μ m (80%), and resolved within 2 months (91%). Topical anti-inflammatory drops were used in 7 of 11 cases, and dorzolamide was used in one case.
CONCLUSION Full-thickness macular holes can develop in eyes without the presence of vitreomacular traction. Topical therapy without vitrectomy may be particularly helpful in closure of full-thickness macular holes with associated cystoid macular edema. Holes with a lamellar hole component may spontaneously resolve as part of a retinal remodeling process.