PubMed ID: 25056608 Author(s): Minella AL, Mowat FM, Willett KL, Sledge D, Bartoe JT, Bennett J, Petersen-Jones SM. Differential targeting of feline photoreceptors by recombinant adeno-associated viral vectors: implications for preclinical gene therapy trials. Gene …
Freya Mowat
Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach.
PubMed ID: 24225638 Author(s): Mowat FM, Gornik KR, Dinculescu A, Boye SL, Hauswirth WW, Petersen-Jones SM, Bartoe JT. Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach. …
Successful gene therapy in older Rpe65-deficient dogs following subretinal injection of an adeno-associated vector expressing RPE65.
PubMed ID: 24028205 Author(s): Annear MJ, Mowat FM, Bartoe JT, Querubin J, Azam SA, Basche M, Curran PG, Smith AJ, Bainbridge JW, Ali RR, Petersen-Jones SM. Successful gene therapy in older Rpe65-deficient dogs following subretinal …
RPE65 gene therapy slows cone loss in Rpe65-deficient dogs.
PubMed ID: 22951453 Author(s): Mowat FM, Breuwer AR, Bartoe JT, Annear MJ, Zhang Z, Smith AJ, Bainbridge JW, Petersen-Jones SM, Ali RR. RPE65 gene therapy slows cone loss in Rpe65-deficient dogs. Gene Ther. 2013 May;20(5):545-55. …
Evaluation of lateral spread of transgene expression following subretinal AAV-mediated gene delivery in dogs.
PubMed ID: 23560080 Author(s): Bruewer AR, Mowat FM, Bartoe JT, Boye SL, Hauswirth WW, Petersen-Jones SM. Evaluation of lateral spread of transgene expression following subretinal AAV-mediated gene delivery in dogs. PLoS One. 2013;8(4):e60218. doi: 10.1371/journal.pone.0060218. …
Bilateral uveal metastasis of a subcutaneous fibrosarcoma in a cat.
PubMed ID: 22360781 Author(s): Mowat FM, Langohr IM, Bilyk O, Koterbay A, Pierce KE, Petersen-Jones SM. Bilateral uveal metastasis of a subcutaneous fibrosarcoma in a cat. Vet Ophthalmol. 2012 Nov;15(6):391-7. doi: 10.1111/j.1463-5224.2012.00993.x. Epub 2012 Feb …
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development.
PubMed ID: 22627278 Author(s): Lange CA, Luhmann UF, Mowat FM, Georgiadis A, West EL, Abrahams S, Sayed H, Powner MB, Fruttiger M, Smith AJ, Sowden JC, Maxwell PH, Ali RR, Bainbridge JW. Von Hippel-Lindau protein …
Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy.
PubMed ID: 22342523 Author(s): Mowat FM, Gonzalez F, Luhmann UF, Lange CA, Duran Y, Smith AJ, Maxwell PH, Ali RR, Bainbridge JW. Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy. Am J Pathol. 2012 Apr;180(4):1726-39. …
Gene augmentation trials using the Rpe65-deficient dog: contributions towards development and refinement of human clinical trials.
PubMed ID: 22183331 Author(s): Petersen-Jones SM, Annear MJ, Bartoe JT, Mowat FM, Barker SE, Smith AJ, Bainbridge JW, Ali RR. Gene augmentation trials using the Rpe65-deficient dog: contributions towards development and refinement of human clinical …