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Kimberly Stepien

Adaptive Optics Imaging Uncovers Photoreceptor Alterations Underlying Visual Distortion After Cystoid Macular Edema.

Posted on December 26, 2025

PubMed ID: 41459033 Author(s): Khoussine J, Arthur P, Rogers J, Stangel N, Stepien KE, Chang JS. Adaptive Optics Imaging Uncovers Photoreceptor Alterations Underlying Visual Distortion After Cystoid Macular Edema. J Vitreoretin Dis. 2025 Dec 26:24741264251404745. …

Posted in Jonathan Chang, Kimberly Stepien, Publications

CLARICO

Posted on July 29, 2025

A Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outcomes of OpCT-001 in up to approximately 54 adults with primary photoreceptor (PR) disease.

Posted in Actively Recruiting, Clinical Trials, Kimberly Stepien

LUNA

Posted on February 6, 2025

B-421a-006 is a 24-month, double-masked, randomized, sham-controlled, multicenter study to evaluate the safety, tolerability, and efficacy of ultevursen in subjects with RP due to mutations in exon 13 of the USH2A gene.

Posted in Clinical Trials, Kimberly StepienTagged clinical trials, Inherited Retinal Diseases, Kimberly Stepien

Characteristics and Predictors of Pediatric and Adult Patients with Inherited Retinal Degenerations: Tertiary Care Ophthalmology Clinic Data.

Posted on January 1, 2025

PubMed ID: 41499610 Author(s): Trudrung MA, McLaughlin MT, Ganansky CP, Taher AW, Van De Car W, Le J, Peterson KD, Stepien KE, Schmitt MA. Characteristics and Predictors of Pediatric and Adult Patients with Inherited Retinal …

Posted in Kimberly Stepien, Melanie Schmitt, Publications

A Prospective, Observational, Non-interventional Clinical Study of Participants With Choroideremia: The NIGHT Study.

Posted on July 1, 2024

PubMed ID: 38311152 Author(s): Maclaren RE, Lam BL, Fischer MD, Holz FG, Pennesi ME, Birch DG, Sankila EM, Meunier IA, Stepien KE, Sallum JMF, Li J, Yoon D, Panda S, Gow JA; NIGHT Study Group. …

Posted in Kimberly Stepien, Publications

POLARIS

Posted on March 2, 2024

An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ATP Binding Cassette Subfamily A Member 4 (ABCA4) Gene (POLARIS)

Posted in Actively Recruiting, Clinical Trials, Kimberly Stepien, Stargardt Disease

NAC Attack

Posted on December 20, 2023

NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double-Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients with Retinitis Pigmentosa.

Posted in Actively Recruiting, Clinical Trials, Inherited Retinal Degeneration, Kimberly Stepien, Retinitis Pigmentosa

UNI-RARE

Posted on December 20, 2023

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated with Rare Disease-Causing Genetic Variants.

Posted in Actively Recruiting, Clinical Trials, Inherited Retinal Degeneration, Kimberly Stepien, Retinal Dystrophy

UNI-RARE

Posted on September 1, 2023

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated with Rare Disease-Causing Genetic Variants

Posted in Actively Recruiting, Clinical Trials, Kimberly Stepien
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