PubMed ID: 33426618 Author(s): Grosser JA, Maes ME, Nickells RW. Characteristics of intracellular propagation of mitochondrial BAX recruitment during apoptosis. Apoptosis. 2021 Feb;26(1-2):132-145. doi: 10.1007/s10495-020-01654-w. Epub 2021 Jan 11. PMID 33426618 Journal: Apoptosis : An …
Nickells Lab
Targeting HDAC3 in the DBA/2J spontaneous mouse model of glaucoma.
PubMed ID: 32971093 Author(s): Schmitt HM, Grosser JA, Schlamp CL, Nickells RW. Targeting HDAC3 in the DBA/2J spontaneous mouse model of glaucoma. Exp Eye Res. 2020 Nov;200:108244. doi: 10.1016/j.exer.2020.108244. Epub 2020 Sep 21. PMID 32971093 …
BAX-Depleted Retinal Ganglion Cells Survive and Become Quiescent Following Optic Nerve Damage.
PubMed ID: 31673950 Author(s): Donahue RJ, Maes ME, Grosser JA, Nickells RW. BAX-depleted retinal ganglion cells survive and become quiescent following optic nerve damage. Mol Neurobiol. 2020 Feb;57(2):1070-1084. doi: 10.1007/s12035-019-01783-7. Epub 2019 Oct 31. PMID …
Completion of BAX recruitment correlates with mitochondrial fission during apoptosis.
PubMed ID: 31719602 Author(s): Maes ME, Grosser JA, Fehrman RL, Schlamp CL, Nickells RW. Completion of BAX recruitment correlates with mitochondrial fission during apoptosis. Sci Rep. 2019 Nov 12;9(1):16565. doi: 10.1038/s41598-019-53049-w. PMID 31719602 Journal: Scientific …
Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury.
PubMed ID: 29211617 Author(s): Schmitt HM, Schlamp CL, Nickells RW. Targeting HDAC3 activity with RGFP966 protects against retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury. J Ocul Pharmacol Ther. 2018 Apr;34(3):260-273. doi: …
AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury.
PubMed ID: 29204649 Author(s): Nickells RW, Schmitt HM, Maes ME, Schlamp CL. AAV2-mediated transduction of the mouse retina after optic nerve injury. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6091-6104. doi: 10.1167/iovs.17-22634. PMID 29204649 Journal: Investigative …
Negative regulators of angiogenesis: important targets for treatment of exudative AMD.
PubMed ID: 28679845 Author(s): Farnoodian M, Wang S, Dietz J, Nickells RW, Sorenson CM, Sheibani N. Negative regulators of angiogenesis: important targets for treatment of exudative AMD. Clin Sci (Lond). 2017 Jul 5;131(15):1763-1780. doi: 10.1042/CS20170066. …
Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system.
PubMed ID: 29386873 Author(s): Donahue RJ, Moller-Trane R, Nickells RW. Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system. Mol Vis. 2017 …
Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis.
PubMed ID: 28880942 Author(s): Maes ME, Schlamp CL, Nickells RW. Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis. PLoS One. 2017 Sep 7;12(9):e0184434. doi: 10.1371/journal.pone.0184434. eCollection 2017. PMID 28880942 Journal: Plo S …