PubMed ID: 33426618 Author(s): Grosser JA, Maes ME, Nickells RW. Characteristics of intracellular propagation of mitochondrial BAX recruitment during apoptosis. Apoptosis. 2021 Feb;26(1-2):132-145. doi: 10.1007/s10495-020-01654-w. Epub 2021 Jan 11. PMID 33426618 Journal: Apoptosis : An …
Nickells Lab
Targeting HDAC3 in the DBA/2J spontaneous mouse model of glaucoma.
PubMed ID: 32971093 Author(s): Schmitt HM, Grosser JA, Schlamp CL, Nickells RW. Targeting HDAC3 in the DBA/2J spontaneous mouse model of glaucoma. Exp Eye Res. 2020 Nov;200:108244. doi: 10.1016/j.exer.2020.108244. Epub 2020 Sep 21. PMID 32971093 …
BAX-Depleted Retinal Ganglion Cells Survive and Become Quiescent Following Optic Nerve Damage.
PubMed ID: 31673950 Author(s): Donahue RJ, Maes ME, Grosser JA, Nickells RW. BAX-depleted retinal ganglion cells survive and become quiescent following optic nerve damage. Mol Neurobiol. 2020 Feb;57(2):1070-1084. doi: 10.1007/s12035-019-01783-7. Epub 2019 Oct 31. PMID …
Completion of BAX recruitment correlates with mitochondrial fission during apoptosis.
PubMed ID: 31719602 Author(s): Maes ME, Grosser JA, Fehrman RL, Schlamp CL, Nickells RW. Completion of BAX recruitment correlates with mitochondrial fission during apoptosis. Sci Rep. 2019 Nov 12;9(1):16565. doi: 10.1038/s41598-019-53049-w. PMID 31719602 Journal: Scientific …
Robert Nickells, PhD, Receives Grant Award from BrightFocus Foundation
BrightFocus Foundation Honors Six Vision Researchers Awards New Grants to Study Macular Degeneration and Glaucoma BrightFocus Foundation today recognized six scientists studying macular degeneration and glaucoma, awarding research grants named in honor of leaders …
Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury.
PubMed ID: 29211617 Author(s): Schmitt HM, Schlamp CL, Nickells RW. Targeting HDAC3 activity with RGFP966 protects against retinal ganglion cell nuclear atrophy and apoptosis after optic nerve injury. J Ocul Pharmacol Ther. 2018 Apr;34(3):260-273. doi: …
AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury.
PubMed ID: 29204649 Author(s): Nickells RW, Schmitt HM, Maes ME, Schlamp CL. AAV2-mediated transduction of the mouse retina after optic nerve injury. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6091-6104. doi: 10.1167/iovs.17-22634. PMID 29204649 Journal: Investigative …
Negative regulators of angiogenesis: important targets for treatment of exudative AMD.
PubMed ID: 28679845 Author(s): Farnoodian M, Wang S, Dietz J, Nickells RW, Sorenson CM, Sheibani N. Negative regulators of angiogenesis: important targets for treatment of exudative AMD. Clin Sci (Lond). 2017 Jul 5;131(15):1763-1780. doi: 10.1042/CS20170066. …
Nickells Lab Explores the Molecular Complexities of Retinal Ganglion Cell Death in Glaucoma
January is National Glaucoma Awareness Month Meet Robert Nickells, PhD, a researcher in the University of Wisconsin Department of Ophthalmology and Visual Sciences. Dr. Nickells leads an active research program studying the biology of …