PubMed ID: 26733303 Author(s): Schmitt HM, Schlamp CL, Nickells RW. Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells. Neurosci Lett. 2016 Jun 20;625:11-5. doi: 10.1016/j.neulet.2015.12.012. Epub 2015 Dec 28. Review. …
Nickells Lab
Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways.
PubMed ID: 27126275 Author(s): Mac Nair CE, Schlamp CL, Montgomery AD, Shestopalov VI, Nickells RW. Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways. J Neuroinflammation. …
Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration.
PubMed ID: 25999234 Author(s): Nickells RW, Pelzel HR. Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration. Exp Eye Res. 2015 Dec;141:99-110. doi: 10.1016/j.exer.2015.05.009. Epub 2015 May 19. Review. PMID 25999234 Journal: Experimental …
The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy.
PubMed ID: 26393670 Author(s): Nickells RW. The long-term effects on the retina damaged by optic nerve axotomy. Invest Ophthalmol Vis Sci. 2015 Sep;56(10):6113. doi: 10.1167/iovs.15-17997. PMID 26393670 Journal: Investigative Ophthalmology & Visual Science, Volume 56, …
Neuroinflammation in Glaucoma and Optic Nerve Damage.
PubMed ID: 26310164 Author(s): Mac Nair CE, Nickells RW. Neuroinflammation in glaucoma and optic nerve damage. Prog Mol Biol Transl Sci. 2015;134:343-63. doi: 10.1016/bs.pmbts.2015.06.010. Epub 2015 Jul 10. Review. PMID 26310164 Journal: Progress In Molecular …
Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush.
PubMed ID: 25407441 Author(s): Mac Nair CE, Fernandes KA, Schlamp CL, Libby RT, Nickells RW. Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush. J Neuroinflammation. 2014 …
Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury.
PubMed ID: 25261965 Author(s): Schmitt HM, Pelzel HR, Schlamp CL, Nickells RW. Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury. Mol Neurodegener. 2014 Sep 28;9:39. …
Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage.
PubMed ID: 24699552 Author(s): Dietz JA, Maes ME, Huang S, Yandell BS, Schlamp CL, Montgomery AD, Allingham RR, Hauser MA, Nickells RW. Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL …
Nuclear atrophy of retinal ganglion cells precedes the bax-dependent stage of apoptosis.
PubMed ID: 23422829 Author(s): Janssen KT, Mac Nair CE, Dietz JA, Schlamp CL, Nickells RW. Nuclear atrophy of retinal ganglion cells precedes the bax-dependent stage of apoptosis. Invest Ophthalmol Vis Sci. 2013 Mar 11;54(3):1805-15. doi: …