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Nickells Lab

Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system.

Posted on January 1, 2017

PubMed ID: 29386873 Author(s): Donahue RJ, Moller-Trane R, Nickells RW. Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system. Mol Vis. 2017 …

Posted in Nickells Lab, Publications

Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis.

Posted on January 1, 2017

PubMed ID: 28880942 Author(s): Maes ME, Schlamp CL, Nickells RW. Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis. PLoS One. 2017 Sep 7;12(9):e0184434. doi: 10.1371/journal.pone.0184434. eCollection 2017. PMID 28880942 Journal: Plo S …

Posted in Nickells Lab, Publications

Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells.

Posted on June 20, 2016

PubMed ID: 26733303 Author(s): Schmitt HM, Schlamp CL, Nickells RW. Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells. Neurosci Lett. 2016 Jun 20;625:11-5. doi: 10.1016/j.neulet.2015.12.012. Epub 2015 Dec 28. Review. …

Posted in Nickells Lab, Publications

Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways.

Posted on April 28, 2016

PubMed ID: 27126275 Author(s): Mac Nair CE, Schlamp CL, Montgomery AD, Shestopalov VI, Nickells RW. Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways. J Neuroinflammation. …

Posted in Nickells Lab, Publications

Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration.

Posted on December 1, 2015

PubMed ID: 25999234 Author(s): Nickells RW, Pelzel HR. Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration. Exp Eye Res. 2015 Dec;141:99-110. doi: 10.1016/j.exer.2015.05.009. Epub 2015 May 19. Review. PMID 25999234 Journal: Experimental …

Posted in Nickells Lab, Publications

The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy.

Posted on September 1, 2015

PubMed ID: 26393670 Author(s): Nickells RW. The long-term effects on the retina damaged by optic nerve axotomy. Invest Ophthalmol Vis Sci. 2015 Sep;56(10):6113. doi: 10.1167/iovs.15-17997. PMID 26393670 Journal: Investigative Ophthalmology & Visual Science, Volume 56, …

Posted in Nickells Lab, Publications

Neuroinflammation in Glaucoma and Optic Nerve Damage.

Posted on January 1, 2015

PubMed ID: 26310164 Author(s): Mac Nair CE, Nickells RW. Neuroinflammation in glaucoma and optic nerve damage. Prog Mol Biol Transl Sci. 2015;134:343-63. doi: 10.1016/bs.pmbts.2015.06.010. Epub 2015 Jul 10. Review. PMID 26310164 Journal: Progress In Molecular …

Posted in Nickells Lab, Publications

Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush.

Posted on November 19, 2014

PubMed ID: 25407441 Author(s): Mac Nair CE, Fernandes KA, Schlamp CL, Libby RT, Nickells RW. Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush. J Neuroinflammation. 2014 …

Posted in Nickells Lab, Publications

Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury.

Posted on September 28, 2014

PubMed ID: 25261965 Author(s): Schmitt HM, Pelzel HR, Schlamp CL, Nickells RW. Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury. Mol Neurodegener. 2014 Sep 28;9:39. …

Posted in Nickells Lab, Publications
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