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Nickells Lab

Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage.

Posted on January 1, 2014

PubMed ID: 24699552 Author(s): Dietz JA, Maes ME, Huang S, Yandell BS, Schlamp CL, Montgomery AD, Allingham RR, Hauser MA, Nickells RW. Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL …

Posted in Nickells Lab, Publications

Nuclear atrophy of retinal ganglion cells precedes the bax-dependent stage of apoptosis.

Posted on March 11, 2013

PubMed ID: 23422829 Author(s): Janssen KT, Mac Nair CE, Dietz JA, Schlamp CL, Nickells RW. Nuclear atrophy of retinal ganglion cells precedes the bax-dependent stage of apoptosis. Invest Ophthalmol Vis Sci. 2013 Mar 11;54(3):1805-15. doi: …

Posted in Nickells Lab, Publications

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death.

Posted on March 5, 2013

PubMed ID: 23431148 Author(s): Welsbie DS, Yang Z, Ge Y, Mitchell KL, Zhou X, Martin SE, Berlinicke CA, Hackler L Jr, Fuller J, Fu J, Cao LH, Han B, Auld D, Xue T, Hirai S, …

Posted in Nickells Lab, Publications

Evaluation of the percentage of ganglion cells in the ganglion cell layer of the rodent retina.

Posted on January 1, 2013

PubMed ID: 23825918 Author(s): Schlamp CL, Montgomery AD, Mac Nair CE, Schuart C, Willmer DJ, Nickells RW. Evaluation of the percentage of ganglion cells in the ganglion cell layer of the rodent retina. Mol Vis. …

Posted in Nickells Lab, Publications

The effect of glial fibrillary acidic protein expression on neurite outgrowth from retinal explants in a permissive environment.

Posted on December 22, 2012

PubMed ID: 23259929 Author(s): Toops KA, Hagemann TL, Messing A, Nickells RW. The effect of glial fibrillary acidic protein expression on neurite outgrowth from retinal explants in a permissive environment. BMC Res Notes. 2012 Dec …

Posted in Nickells Lab, Publications

The cell and molecular biology of glaucoma: mechanisms of retinal ganglion cell death.

Posted on May 4, 2012

PubMed ID: 22562845 Author(s): Nickells RW. The cell and molecular biology of glaucoma: mechanisms of retinal ganglion cell death. Invest Ophthalmol Vis Sci. 2012 May 4;53(5):2476-81. doi: 10.1167/iovs.12-9483h. PMID 22562845 Journal: Investigative Ophthalmology & Visual …

Posted in Nickells Lab, Publications

Hydrocortisone stimulates neurite outgrowth from mouse retinal explants by modulating macroglial activity.

Posted on April 24, 2012

PubMed ID: 22395888 Author(s): Toops KA, Berlinicke C, Zack DJ, Nickells RW. Hydrocortisone stimulates neurite outgrowth from mouse retinal explants by modulating macroglial activity. Invest Ophthalmol Vis Sci. 2012 Apr 24;53(4):2046-61. doi: 10.1167/iovs.11-8646. PMID 22395888 …

Posted in Nickells Lab, Publications

The potential role of epigenetics in ocular diseases.

Posted on April 1, 2012

PubMed ID: 22491920 Author(s): Nickells RW, Merbs SL. The potential role of epigenetics in ocular diseases. Arch Ophthalmol. 2012 Apr;130(4):508-9. doi: 10.1001/archopthalmol.2011.1423. PMID 22491920 Journal: Archives Of Ophthalmology (Chicago, Ill. : 1960), Volume 130, Issue …

Posted in Nickells Lab, Publications

Silencing of Fem1cR3 gene expression in the DBA/2J mouse precedes retinal ganglion cell death and is associated with histone deacetylase activity.

Posted on March 1, 2012

PubMed ID: 22297488 Author(s): Pelzel HR, Schlamp CL, Waclawski M, Shaw MK, Nickells RW. Silencing of Fem1cR3 gene expression in the DBA/2J mouse precedes retinal ganglion cell death and is associated with histone deacetylase activity. …

Posted in Nickells Lab, Publications
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