PubMed ID: 36445243 Author(s): Wang Y, Wang X, Xie R, Burger JC, Tong Y, Gong S. Overcoming the Blood-Brain Barrier for Gene Therapy via Systemic Administration of GSH-Responsive Silica Nanocapsules. Adv Mater. 2023 Feb;35(6):e2208018. doi: …
Shaoqin Gong
Efficient in vivo neuronal genome editing in the mouse brain using nanocapsules containing CRISPR-Cas9 ribonucleoproteins.
PubMed ID: 36527789 Author(s): Metzger JM, Wang Y, Neuman SS, Snow KJ, Murray SA, Lutz CM, Bondarenko V, Felton J, Gimse K, Xie R, Li D, Zhao Y, Flowers MT, Simmons HA, Roy S, Saha …
Non-viral approaches for gene therapy and therapeutic genome editing across the blood-brain barrier.
PubMed ID: 37485250 Author(s): Xie R, Wang Y, Burger JC, Li D, Zhu M, Gong S. Non-viral approaches for gene therapy and therapeutic genome editing across the blood-brain barrier. Med X. 2023;1(1):6. doi: 10.1007/s44258-023-00004-0. Epub …
Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors.
PubMed ID: 37564994 Author(s): Neuman SS, Metzger JM, Bondarenko V, Wang Y, Felton J, Levine JE, Saha K, Gong S, Emborg ME. Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors. Front …
Multifunctional nanoparticle potentiates the in situ vaccination effect of radiation therapy and enhances response to immune checkpoint blockade.
PubMed ID: 35999216 Author(s): Zhang Y, Sriramaneni RN, Clark PA, Jagodinsky JC, Ye M, Jin W, Wang Y, Bates A, Kerr CP, Le T, Allawi R, Wang X, Xie R, Havighurst TC, Chakravarty I, Rakhmilevich …
NAD(H)-loaded nanoparticles for efficient sepsis therapy via modulating immune and vascular homeostasis.
PubMed ID: 35668170 Author(s): Ye M, Zhao Y, Wang Y, Xie R, Tong Y, Sauer JD, Gong S. NAD(H)-loaded nanoparticles for efficient sepsis therapy via modulating immune and vascular homeostasis. Nat Nanotechnol. 2022 Aug;17(8):880-890. doi: …
New nanoparticles aid sepsis treatment in mice
Tens of millions of people worldwide are affected by diseases like macular degeneration or have had accidents that permanently damage the light-sensitive photoreceptors within their retinas that enable vision.
pH-Responsive Polymer Nanoparticles for Efficient Delivery of Cas9 Ribonucleoprotein With or Without Donor DNA.
PubMed ID: 35119139 Author(s): Xie R, Wang X, Wang Y, Ye M, Zhao Y, Yandell BS, Gong S. pH-Responsive Polymer Nanoparticles for efficient delivery of Cas9 Ribonucleoprotein with or without Donor DNA. Adv Mater. 2022 …
Ultrasound-activable piezoelectric membranes for accelerating wound healing.
PubMed ID: 34919105 Author(s): Shi X, Chen Y, Zhao Y, Ye M, Zhang S, Gong S. Ultrasound-activable piezoelectric membranes for accelerating wound healing. Biomater Sci. 2022 Feb 1;10(3):692-701. doi: 10.1039/d1bm01062j. PMID 34919105 Journal: Biomaterials Science, …