A method for overcoming antibiotic resistance uses multimodal nanoparticles that target bacterial defence mechanisms while enhancing the innate immune response. The rise in antibiotic resistance is considered a slow-moving medical catastrophe, as these revolutionary drugs that have kept us relatively safe from bacterial infection for decades are losing their efficacy. In part due to their co-evolution, bacterial pathogens have developed mechanisms to resist almost every antibiotic on the market and we are in desperate need for new, innovative approaches. Writing in Nature Nanotechnology, Zhu et al. present a nanoparticle-based possibility, in which they target bacterial defence mechanisms while simultaneously enhancing the ability of the host immune cells to fight infection.
Research News
Introducing the 2024 Kambara Symposium Keynote Speaker: Budd Tucker, PhD
A highly accomplished vision scientist and expert in retinal disease will be the keynote speaker at the 2023 George Kambara, MD Vision Science Symposium on Friday, April 14, 2024.
New Vision Research Utilizes “Cell” Sequencing to Shed Light on Childhood Glaucoma
Stuart Tompson, PhD and colleagues at the University of Wisconsin—Madison are exploring a novel cell profiling approach to understand Primary Congenital Glaucoma (PCG). PCG is a severe pediatric eye disease affecting 1 in 10,000 infants …
Testing Senses and Motor Skills in Midlife May Help Predict Later Cognitive Impairment
When researchers test motor skills, hearing, vision, and smell in people in their midlife, they are better able to identify those who may develop cognitive decline or impairment 10 years later, according to a new …
Novel Research from UW Vision Scientists Could Offer Hope for the Early Detection of Alzheimer’s Disease
Novel research from scientists in UW-Madison’s Department of Ophthalmology and Visual Sciences may lead to a new, non-invasive method for the early detection of Alzheimer’s Disease.
Knowing What Dogs Like to Watch Could Help Veterinarians Assess Their Vision
Researchers at the University of Wisconsin–Madison have taken a novel approach to assessing canine vision. Their recent study uses a dog’s interest in a variety of video content to better measure the quality of its vision.
New Research Reveals Signs of Glaucoma May Be Detectable Years in Advance of Disease Onset
Groundbreaking research from Yao Liu, MD and colleagues reported that low pigment density in a part of the light-sensing retina called the macula may serve as an early warning sign of glaucoma – suggesting a strategy for the testing and treatment of the disease.
Vision Research Core Receives $3.1 Million Grant
The Vision Research Core has received a $3.1 million grant from the National Eye Institute to provide expertise, facilities, and equipment to foster and expand vision research across the University of Wisconsin-Madison campus.
Big Data, Big Results: UW Selected as Member of IRIS Registry Analytics Consortium
The department is now a member of the American Academy of Ophthalmology’s Intelligent Research in Sight (IRIS) Registry Analytics Consortium. This will allow the access to big data that has the potential to shape future scientific research.