PubMed ID: 23379998 Author(s): Hawthorne FA, Young TL. Genetic contributions to myopic refractive error: Insights from human studies and supporting evidence from animal models. Exp Eye Res. 2013 Sep;114:141-9. doi: 10.1016/j.exer.2012.12.015. Epub 2013 Feb 1. …
Young Lab
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
PubMed ID: 24144296 Author(s): Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, …
Myopia-related fundus changes in Singapore adults with high myopia.
PubMed ID: 23499368 Author(s): Chang L, Pan CW, Ohno-Matsui K, Lin X, Cheung GC, Gazzard G, Koh V, Hamzah H, Tai ES, Lim SC, Mitchell P, Young TL, Aung T, Wong TY, Saw SM. Myopia-related …
Mutations in SCO2 are associated with autosomal-dominant high-grade myopia.
PubMed ID: 23643385 Author(s): Tran-Viet KN, Powell C, Barathi VA, Klemm T, Maurer-Stroh S, Limviphuvadh V, Soler V, Ho C, Yanovitch T, Schneider G, Li YJ, Nading E, Metlapally R, Saw SM, Goh L, Rozen …
Copy number variation at chromosome 5q21.2 is associated with intraocular pressure.
PubMed ID: 23599335 Author(s): Nag A, Venturini C, Hysi PG, Arno M, Aldecoa-Otalora Astarloa E, Macgregor S, Hewitt AW, Young TL, Mitchell P, Viswanathan AC, Mackey DA, Hammond CJ. Copy number variation at chromosome 5q21.2 …
Whole exome sequencing identifies a mutation for a novel form of corneal intraepithelial dyskeratosis.
PubMed ID: 23349227 Author(s): Soler VJ, Tran-Viet KN, Galiacy SD, Limviphuvadh V, Klemm TP, St Germain E, Fournié PR, Guillaud C, Maurer-Stroh S, Hawthorne F, Suarez C, Kantelip B, Afshari NA, Creveaux I, Luo X, …
Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2.
PubMed ID: 23422819 Author(s): Hawthorne F, Feng S, Metlapally R, Li YJ, Tran-Viet KN, Guggenheim JA, Malecaze F, Calvas P, Rosenberg T, Mackey DA, Venturini C, Hysi PG, Hammond CJ, Young TL. Association mapping of …
CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the United States.
PubMed ID: 23218701 Author(s): Lim SH, Tran-Viet KN, Yanovitch TL, Freedman SF, Klemm T, Call W, Powell C, Ravichandran A, Metlapally R, Nading EB, Rozen S, Young TL. CYP1B1, MYOC, and LTBP2 mutations in primary …
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
PubMed ID: 23396134 Author(s): Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, MacGregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp …